Clozapine

2.1 Classification of the substance or mixture

This chemical is considered hazardous by the 2012 OSHA Hazard Communication Standard (29 CFR 1910.1200) Acute oral toxicity Category 3 Skin Corrosion/Irritation Category 2 Serious Eye Damage/Eye Irritation Category 2 Germ Cell Mutagenicity Category 2 Reproductive Toxicity Category 2 Specific target organ toxicity (single exposure) Category 3 Target Organs - Respiratory system.

Signal word

Danger

Hazard statements

Toxic if swallowed Causes skin irritation Causes serious eye irritation May cause respiratory irritation Suspected of causing genetic defects Suspected of damaging fertility or the unborn child

Prevention

Obtain special instructions before use Do not handle until all safety precautions have been read and understood Use personal protective equipment as required Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product Wear eye/face protection Avoid breathing dust/fume/gas/mist/vapors/spray Use only outdoors or in a well-ventilated area

Response

IF exposed or concerned: Get medical attention/advice Inhalation IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing Skin IF ON SKIN: Wash with plenty of soap and water If skin irritation occurs: Get medical advice/attention Take off contaminated clothing and wash before reuse Eyes IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing If eye irritation persists: Get medical advice/attention Ingestion IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician Rinse mouth

Storage

Store locked up Store in a well-ventilated place. Keep container tightly closed

Disposal

Dispose of contents/container to an approved waste disposal plant

2.3 Other hazards

None identified