2-Methoxyestradiol

2.1 Classification of the substance or mixture

WHMIS 2015 Classification Classified as hazardous under the Hazardous Products Regulations (SOR/2015-17) Acute oral toxicity Category 3 Acute dermal toxicity Category 3 Acute Inhalation Toxicity Category 3 Skin Corrosion/Irritation Category 2 Serious Eye Damage/Eye Irritation Category 2 Carcinogenicity Category 1B Reproductive Toxicity Category 1B Specific target organ toxicity (single exposure) Category 3 Target Organs - Respiratory system. Specific target organ toxicity - (repeated exposure) Category 1

Signal word

Danger

Hazard statements

Toxic if swallowed, in contact with skin or if inhaled Causes skin irritation Causes serious eye irritation May cause respiratory irritation May cause cancer May damage fertility or the unborn child Causes damage to organs through prolonged or repeated exposure

Prevention

Obtain special instructions before use Do not handle until all safety precautions have been read and understood Do not breathe dust/fumes/gas/mist/vapours/spray Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product Use only outdoors or in a well-ventilated area Wear protective gloves/protective clothing/eye protection/face protection

Response

Wash contaminated clothing before reuse IF SWALLOWED: Immediately call a POISON CENTER/doctor IF ON SKIN: Wash with plenty of soap and water IF INHALED: Remove person to fresh air and keep comfortable for breathing IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing IF exposed or concerned: Get medical advice/attention Call a POISON CENTER/ doctor Rinse mouth Take off immediately all contaminated clothing

Storage

Store locked up Store in a well-ventilated place. Keep container tightly closed

Disposal

Dispose of contents/container to an approved waste disposal plant

2.3 Other hazards

Very toxic to aquatic life with long lasting effects