Note: Ingredients listed on restricted chemical lists
EC/CAS
200-413-8
Name of the chemical
Methotrexate (INN)
Concentration
100%
General Information
Version
6.3
Revision date
2025-01-22
Product name
Methotrexate
CAS No.
59-05-2
REACH No
NA
1.2.1 Relevant identified uses
Active pharmaceutical ingredients
supplier name
VAT Reg. No
Emergency telephone
+358 800 147111, +358 9 471 977
Icons in SDS
Company Information
company name
Fermion Oy
e-mail address of the competent person responsible for the Safety Data Sheet
chemicalsafety@orion.fi
GHS Information
Signal word
Danger
Hazard Codes
Hazard statements (CLP)
H301, H315, H319, H335, H340, H351, H360D
Hazard statements
Code
Statements
H301
Toxic if swallowed
Section 2
SECTION 2: Hazards identification
Regulation (EC) No. 1272/2008 Classification of the substance or mixture
Signal word
Danger
Hazard statements
H301 Toxic if swallowed. H351 Suspected of causing cancer. H340 May cause genetic defects. H360D May damage the unborn child. H319 Causes serious eye irritation. H315 Causes skin irritation. H335 May cause respiratory irritation.
Precautionary statements
General: P280 Wear protective gloves/ protective clothing/ eye protection/ face protection. P261 Avoid breathing dust/ fume/ gas/ mist/ vapors/ spray. P301 + P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/ physician. P308 + P313 IF exposed or concerned: Get medical advice/ attention. P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P501 Dispose of contents according to national and local law.
Other hazards
No data available
PBT Substances
No data available
vPvB Substances
No data available Endocrine disrupting pro-
ECOLOGICAL INFORMATION
No data available perties
TOXICOLOGICAL INFORMATION
No data available
2.1 Classification of the substance or mixture
Classification (REGULATION (EC) No 1272/2008) Acute toxicity, Category 3 H301: Toxic if swallowed. Germ cell mutagenicity, Category 1B H340: May cause genetic defects. Reproductive toxicity, Category 1B H360D: May damage the unborn child. Eye irritation, Category 2 H319: Causes serious eye irritation. Skin irritation, Category 2 H315: Causes skin irritation. Carcinogenicity, Category 2 H351: Suspected of causing cancer. Specific target organ toxicity - single ex- H335: May cause respiratory irritation. posure, Category 3, Respiratory system For explanation of abbreviations see section 16.
