WeedWHACKER Herbicide

SECTION 2: Hazards identification

Main hazard: Very toxic to aquatic organisms, may cause long term adverse effects in the aquatic environment. Poisonous if swallowed. May irritate the nose, skin, throat and eyes. Do not contaminate rivers, streams or dams (very toxic to aquatic organisms). Do not apply within the root zone of desirable vegetation. Flammability: Non flammable and non-volatile when diluted for use. Chemical hazard: Bromacil

Most important adverse effects

No hazards to be especially mentioned Biological hazard: Highly toxic to algae. Very toxic to aquatic organisms, may cause long term adverse effects in the aquatic environment. Bromacil can seep or leach through soil and can enter ground water which may be used as drinking water. Correct use rates by geographical area and proper mixing-loading site precautions and procedures must be followed to minimize potential Bromacil movement into ground water. Reproductive hazard: Bromacil did not affect the reproduction and lactation performance of rats fed 0 or 12.5 mg/kg/day for 3 generations. Eye effects: eyes: Bromacil – Mild to moderate eye irritant causing mild corneal opacity. Product – risk of serious damage to eyes (dye in product).

Health Effects - Skin

Bromacil – Dermal LD50 (rat)>5000 mg/kg; the compound is a moderate skin irritant. It is not a skin sensitizer.

Potential health effects

ingestion Bromacil – Oral LD50 (rat) = 5175 mg/kg. When a massive dose was administered to the dog (5 000 mg/kg), incoordination, salivation, vomiting, weakness, lacrimination and dilated pupils were observed. Toxicity described in animals repeatedly exposed to near lethal doses include liver changes, increased liver, adrenal and heart weights, decreased kidney and spleen weights. See section 4: Product ingested. inhalation Bromacil – LD50(4 h) for rats > 4.8 mg/ℓ air; Irritating to respiratory system. All rats tolerated a 4-hr. exposure at the equivalent of 4800 mg/m3 (4.8 mg/ℓ) indicating a low order of acute inhalation toxicity. Higher concentrations were impractical under test conditions. Product: Avoid inhalation of spray mist. Do not breath gas/ fumes/ vapour/spraymist/dust. Carcinogenic: Bromacil 24 month dietary rat NOEL 50 ppm; not oncogenic; body weight effects at ≥250 ppm. Although bromacil has not been determined to cause cancer, it is considered by the EPA to be a possible human carcinogen because there is some limited or uncertain evidence that bromacil cause cancer in animals receiving high doses of the chemical over the course of their lifetimes. There was no evidence of carcinogenicity in rats fed 12.5 mg/kg/day of bromacil. Mutagenicity: Bromacil Gene mutation Ames test, negative; CHO/HGPRT negative. Structural chromosome aberration mouse micro-nucleus, negative. In vitro cytogenetics, clastogenic. DNA damage/repair: UDS, negative. Several mutagenic screening tests have not found Bromacil to be mutagenic. Neurotoxicity: Ingestion of very LARGE AMOUNTS may cause CNS depression. 4. FIRST AID MEASURES AND PRECAUTIONS Product in eye: Flush immediately with clear clean running water for about 15 minutes. Hold eyelids apart to rinse the entire surface of the eye and lids. Call a physician. If eye symptoms (redness, irritation or pain) persist refer patient to ophthalmologist for examination of eye.