Vasostrict (vasopressin injection, USP)

SECTION 2: Hazards identification

(29 CFR 1910.1200) Classification of the Substance or Mixture GHS-US/CA Classification Not classified

2.2 Label elements

GHS-US/CA Labeling

2.3 Other hazards

Exposure may aggravate pre-existing eye, skin, or respiratory conditions. Vasopressin is a potent antidiuretic and vasoconstricting agent. The most common adverse effects reported with use (up to ~100 µg/day) include marked pallor, pounding headache, vertigo, sweating, tremor, and gastrointestinal disturbances (nausea, vomiting, diarrhea, burping, cramps, and a desire to defecate). Women reported uterine cramps/contractions. A syndrome similar to water intoxication (characterized by listlessness, drowsiness, headache, and confusion, with subsequent seizures, coma, and death) has also been reported. Consistent with its activity, the drug may increase blood pressure, slow heart rate, and instigate other cardiovascular effects (e.g, heart block, minor arrhythmias, coronary insufficiency, and heart attack). Hypersensitivity reactions have also occurred. Based on its ability to cause uterine contractions and non-clinical study results described below, vasopressin may adversely affect pregnancy and/or a developing fetus.

Ingredient(s) with unknown acute toxicity

No additional information available

2.1 Classification of the substance or mixture

GHS-US/CA Classification Not classified.