General Information
Revision date
2017-06-01
Product name
HYDROCORTISONE, USP (Micronized)
Product Synonyms
11-beta-Hydrocortisone, 11-beta-Hydroxycortisone, Dihydrocortisone
CAS No.
50-23-7
1.2.1 Relevant identified uses
Glucocorticoid; anti-inflammatory (Hormone)
supplier name
Encore Scientific
Emergency telephone
(800) 535-5053 (Within Continental US and Canada); (352)323-3500 (International
Icons in SDS
Company Information
company name
Encore Scientific
GHS Information
Signal word
Danger
Hazard Codes
Hazard statements (CLP)
H361
Hazard statements
Code
Statements
H361
Suspected of damaging fertility or the unborn child
Section 2
EU Classification
Regulation 29 CFR 1910 (OSHA HCS) Toxic to Reproduction (Category 2) Specific Target Organ Toxicity - Repeated Exposure (Category 2) Sensitization - Respiratory (Category 1) Sensitization - Skin (Category 1)
Adverse physicochemical, human health and environmental effects
Reproductive toxicity (Category 2), H361
2.2 Label elements
Labelling according to Regulation 29 CFR 1910 (OSHA HCS)
Signal word
Danger
Hazard statements
Suspected of damaging fertility or the unborn child May cause damage to organs through prolonged or repeated May cause allergy or asthma symptoms or breathing difficulties if inhaled. May cause an allergic skin reaction. Identification (continued)
Precautionary statements
Symptoms: Not expected to present a significant hazard under anticipated conditions of normal use. May cause systemic effects when applied to large areas when the skin is broken or under occlusive dressings; can cause raised intra-ocular pressure and reduced visual function. Clinical use has resulted in changes in electrolytes and/or blood chemistry changes. Drugs of this class may cause Cushing's syndrome, manifested by moon face, obesity, headache, acne, thirst, increased urination, impotence, menstrual irregularities, facial hair growth, and mental changes. Clinical use may cause an increase in blood pressure (hypertension). When applied topically, particularly to large areas, when the skin is broken, or under occlusive dressings, corticosteroids may be absorbed in sufficient amounts to cause systemic effects.
Potential health effects
Inhalation: May be harmful if inhaled. May cause respiratory tract irritation. Ingestion: May be harmful if swallowed. Ingestion of this material may cause effects similar to those seen in clinical use including nausea, vomiting, muscle cramps, weakness, nervousness, restlessness, trouble sleeping. Skin: May be harmful if absorbed through skin. May cause skin irritation Eyes: May cause eye irritation.
Other hazards which do not result in classification
Repeated exposure may cause skin dryness or cracking.
