/ M (+) C M BC RM C details

Hazard statements (CLP)

H317

Code

Statements

H317

May cause an allergic skin reaction

SECTION 2: Hazards identification

hazards which do not Other None known. ingredients position/inform ation on Section 3: Com Substance / M ixture M ixture Chem ical nature potentially infectious. Handle as ponents Com Chem ical nam e CAS -No. Concentration (% w/w ) of: M ixture 5 -chloro -2-m ethyl -4-isothiazolin -3- 55965 -84 -9 >= 0.0025 - < 0.025 and 2 one -m ethyl -2H -isothiazol -3-one (3:1) First -aid m easures General advice dangerous area. M ove out of attendance. safety sheet to the doctor in Show this data victim unattended. Do not leave the If inhaled M ove to fresh air. exposure. physician after significant Consult a seek m edical in recovery position and If unconscious, place advice. case of skin contact In well with water. If on skin, rinse case of eye contact In with water as a precaution. Flush eyes lenses. Rem ove contact eye. Protect unharm ed M BC RM C / (+) 4 open while rinsing. Keep eye wide persists, consult a speciali If eye irritation st. swallowed If tract clear. Keep respiratory alcoholic beverages. Do not give m ilk or unconscious person. m outh to an Never give anything by persist, call a physician. If sym ptom s ost im portant sym ptom s M inhaled. M ay be harm ful if effects, both acute and and allergic skin reaction. M ay cause an delayed to physician Notes established in consultation procedure should be The first aid edicine. responsible for industrial m with the doctor Section 5: Fire -fighting m easures Suitable extinguishing m edia appropriate local m easures that are to Use extinguishing environm and the surounding ent. circum stances Unsuitable extinguishing water High volum e jet m edia Specific during Do not allow run -off or water from fighting to enter drains fire firefighting courses. Hazardous com bustion Carbon oxides products Specific extinguishing separately. This fire extinguishing water Collect contam inated ethods m discharged into drains. m ust not be extinguishing water m ust and contam inated fire Fire residues regulations. accordance with local be disposed of in protective equipm ent Special W ear self -contained firefighting if breathing apparatus for firefighters for necesary. release m easures Accidental Personal

Precautionary statements

personal protective equipm ent. Use protective equipm ent and adequate ventilation. Ensure procedures em ergency 7 and 8. protective m easures listed in sections Refer to Environm ental from entering drains. Prevent product so. leakage or spillage if safe to do Prevent further Local a advised if significant spillages uthorities should be cannot be contained. ethods and m aterials for M sand, silica gel, absorbent m aterial (e.g. Soak up with inert containm ent and cleaning up sawdust). universal binder, acid binder, disposal. closed containers for Keep in suitable, M BC RM C / (+) 5 and

Storage

Handling Advice protection against on protection. for preventive fire Norm al m easures explosion fire and Advice safe handling on of aerosol. Avoid form ation vapours/dust. Do not breathe Avoid exposure - instructions before use. obtain special Avoid contac with skin and eyes. t protection see section 8. For personal prohibited in the drinking should be Sm oking, eating and application area. exhaust in work room s. air exchange and/or Provide sufficient local nation water in acordance with and Dispose of rinse al regulations. problem or asthm a, susceptible skin sensitisation s Persons to disease should not recurent respiratory allergies, chronic or is being process in which this m ixture be em ployed in any used. m easures Hygiene or drink. W hen using do not eat sm oke. W hen using do not of workday. before breaks and at the end W ash hands Conditions for safe well closed in a dry and Keep container tightly -ventilated place. resealed and which are opened m ust be carefully Containers leakage. kept upright to prevent ust com ply with / working m aterials Electrical installations safety standards. the technological inform ation on Further insert or internal guidelines See label, package conditions inform ation on Further directed. if stored and applied as No decom position stability protection controls/personal Exposure control param eters ponents with workplace Com Con exposure lim it values. substances with ocupational tains no Engineering m easures No data available Personal protective equipm ent Respiratory protection with an form ation use a respirator In the case of vapour approved filter. M BC RM C / (+) 6 Hand protection through splashing: In case of contact M aterial Nitrile rubber tim Break through e > 30 m in thickness Glove > 0.11 m contact: In case of full M aterial butyl -rubber tim Break through e > 480 m in thickness Glove > 0.4 m Rem arks satisfy protective gloves have to the The selected standard of Regulation (EU) 2016/425 and the specifications from it. EN 374 derived is only valid for This recom endation sheet and provided in the safety data the product m entioned us. application specified by by us and for the Please observe breakthrough tim e regarding perm eability and the instructions provided the supplier which are by gloves. Also take of the under which specific local conditions into consideration the cuts, abrasion, used, such as the danger of the product is tim and the contact e. workplace suitability for a specific The discused with the producers of p should be rotective gloves. protection Eye pure water Eye wash bottle with safety goggles Tightly fitting body protection Skin and Im pervious clothing and protection according to the am ount Choose body at work place. dangerous substance the concentration of the and chem ical properties Physical Appearance liquid Colour yellow available No data Odour available No data Threshold Odour available No data pH 7.3 point/ range M elting available No data M BC RM C / (+) 7 point/boiling range Boiling available No data point Flash not flash does Evaporation rate available No data Self -ignition available No data Upper explosion lim it / Upper available No data ability lim it flam Lower explosion lim it / Lower available No data ability lim it flam Vapour presure available No data Relative vapour density available No data Relative density available No data Density g/cm 1.026 3 Solubility(ies) solubility W ater pletely m iscible com other solvents Solubility in available No data Partition coefficient: n - available No data octanol/water Auto -ignition tem perature available No data Decom position tem perature available No data Viscosity Viscosity, dynam ic available No data Viscosity, kinem atic available No data properties Oxidizing classified as oxidizing. substance or m ixture is not The reactivity Stability and Reactivity under conditions of norm al use. dangerous reaction known No Chem ical stability under norm al conditions. Stable M BC RM C / (+) 8 Posibility of hazardous applied directed. decom position if stored and as No reactions Conditions to avoid available No data Incom patible m aterials available No data Hazardous decom position available No data products transportat ion, disposal and release is not to be considered a waranty or quality specification. The inform ation relates only to the specific aterial m designated and ay not be valid for such aterial used in com bination with any m aterials or in any proces other s, unles specified in the text. NZ / EN / 2304 M BC RM C / (+) 15 Section 1: Identification Product nam e HIV -1-O / O (+) RM C details anufacturer or supplier's M Com pany Diagnostics NZ Ltd Roche - Addres W ellington Highway 286 M t ellington, Auckland 1060 M t. W AKL Zealand New Telephone 2764157 +64 9 Em ergency telephone num ber case of em ergencies: In Diagnostics NZ Ltd Roche 0800 652 634 Follow Voice Prom pt Poisons Centre National Dunedin http://www.poisons.co.nz Hour Help Line 24 0800 764 766 E-m address ail rdnz.logistics@ roche.com use ical and restrictions on Recom m ended use of the chem Recom ended use Laboratory chem icals details. product literature for further Refer to identification Hazard Classification GHS sensitisation Skin Category 1 elem ents GHS label

TOXICOLOGICAL INFORMATION

Acute toxici ty harm ful if inhaled. M ay be classified due to lack of data. Not Product inhalation toxicity Acute ate Acute toxicity estim 30.03 m g/l Exposure tim e 4 h osphere Test atm vapour M ethod Calculation m ethod ponents Com of: 5 M ixture -chloro -2-m ethyl -4-isothiazolin -3-one and 2 -m ethyl -2H -isothiazol -3-one (3:1) toxicity Acute oral LD50 Oral (Rat , m ale ): g/kg 64 m inhalation toxicity Acute LC50 (Rat , m ale and fem ): 0.33 m g/l Exposure tim e 4 h osphere Test atm dust/m ist M ethod Guideline 403 OECD Test derm al toxicity Acute LD50 Derm al (Rabbit , m ale ): 87.12 m g/kg corrosion/irritation Skin classified due to lack of data. Not Product Rem arks skin iritation and/or derm atitis. M ay cause ponents Com of: 5 M ixture -chloro -2-m ethyl -4-isothiazolin -3-one and 2 -m ethyl -2H -isothiazol -3-one (3:1) Result hours of exposure Corosive after 1 to 4 eye dam age/eye irritation Serious classified due to lack of data. Not M BC RM C / (+) 9 Product Rem arks respiratory system cause iritation to the eyes, Vapours m ay and the skin. ponents Com of: 5 M ixture -chloro -2-m ethyl -4-isothiazolin -3-one and 2 -m ethyl -2H -isothiazol -3-one (3:1) Species Rabbit Result dam to eyes. Risk of serious age sensitisation Respiratory or skin sensitisation Skin classified due to lack of data. Not sensitisation Skin cause an allergic skin reaction. M ay Respiratory sensitisation classified due to lack of data. Not Respiratory sensitisation classified due to lack of data. Not Product Rem arks sensitisation. Causes ponents Com of: 5 M ixture -chloro -2-m ethyl -4-isothiazolin -3-one and 2 -m ethyl -2H -isothiazol -3-one (3:1) Test Type assay (LLNA) Local lym ph node Species M ouse Assesm ent skin sensitiser, sub The product is a -category 1A. toxicity Chronic cell m utagenicity Germ classified due to lack of data. Not Carcinogenicity classified due to lack of data. Not Reproductive toxicity classified due to lack of data. Not STOT - single exposure classified due to lack of data. Not M BC RM C / (+) 10 STOT - repeated exposure Not c of data. lassified due to lack classified due to lack of data. Not Aspiration toxicity classified due to lack of data. Not inform ation Ecological Ecotoxicity ponents Com of: 5 M ixture -chloro -2-m ethyl -4-isothiazolin -3-one and 2 -m ethyl -2H -isothiazol -3-one (3:1) Toxicity to fish LC50 (Oncorhynchus ykiss (rainbow trout) m ): 0.19 m g/l Exposure tim e 96 h Test Type flow -through test Toxicity to daphnia and other EC50 (Daphnia flea) m agna (W ater ): g/l 0.16 m aquatic invertebrates Exposure tim e 48 h Test Type flow -through test Toxicity to algae/aquatic ErC50 (Skeletonem diatom ) costatum (m arine a ): 0.0063 m g/l plants Exposure tim e 72 h Test Type static test M ethod Guideline 201 OECD Test M-Factor (Acute aquatic 100 toxicity ) 100 Toxicity to fish (Chronic NOEC (Cyprinodon (m innow) sp. ): 0.02 m g/l toxicity ) Exposure tim e 38 d Test Type sem i -static test M ethod Guideline 210 OECD Test Toxicity to daphnia and other NOEC (Daphnia flea) (water ): 0.1 m g/l aquatic invertebrates Exposure tim e 21 d (Chronic toxicity ) GLP yes M-Factor (Chronic aquatic 100 toxicity ) 100 Assessm ent Ecotoxicology Toxicity Data on Soil adsorb on soil. Not expected to organism s relevant to Other No data available

Environmental hazards

the M BC RM C / (+) 11 Persistence and degradability ponents Com of: 5 M ixture -chloro -2-m ethyl -4-isothiazolin -3-one and 2 -m ethyl -2H -isothiazol -3-one (3:1) Biodegradability Result biodegradable. Inherently Rem arks not fulfilled. tim window criterion is The 10 day e Result biodegradable. Not readily M ethod Guideline 301B OECD Test GLP yes ulative potential Bioaccum ponents Com of: 5 M ixture -chloro -2-m ethyl -4-isothiazolin -3-one and 2 -m ethyl -2H -isothiazol -3-one (3:1) Bioacum ulation Species (Bluegill sunfish) Lepom is m acrochirus (BCF) Bioconcentration factor 54 Tem perature 20 °C Concentration ca. 0.01 m g/l Partition coefficient: n - log Pow 0.75 octanol/water in soil M obility data available No adverse efects Other Product Additional ecological the event of cannot be excluded in An environm ental ation inform unprofessional handling disposal. or effects. life with long lasting Harm ful to aquatic considerations

Disposal

ethods Disposal m from residues W aste andatory i infectious m aterial is Special treatm ent as n and regulations (disinfection com pliance with local incineration). drains, water should not allowed to enter The product be soil. courses or the or ditches with ponds, waterways Do not contam inate container. chem ical or used licensed waste m ana Send to a gem ent com pany. com pliance with disposed as waste water, when in Can be local regulations. Contam inated packaging contents. Em pty rem aining M BC RM C / (+) 12 unused product. Dispose of as approved waste should be taken to an Em pty containers recycling or disposal. handling site for Do not re -use em pty containers. inform ation Transport International Regulations UNRTD G num UN ber Not applicable Proper shipping nam e Not applicable Class Not applicable Subsidiary risk Not applicable group Packing Not applicable Labels Not applicable IATA -DGR UN/ID No. Not applicable Proper shipping nam e Not applicable Class Not applicable Subsidiary risk Not applicable group Packing Not applicable Labels Not applicable instruction (cargo Packing Not applicable aircraft) instruction Packing Not applicable (pasenger aircraft) IM DG -Code num UN ber Not applicable Proper shipping nam e Not applicable Class Not applicable Subsidiary risk Not applicable group Packing Not applicable Labels Not applicable Em S Code Not applicable pollutant M arine Not applicable Tr 73/78 and the IBC Code Annex II of M ARPOL in bulk according to ansport applicable Not National Regulations NZS 5433 P501 approved waste Dispose of plant. result in

UN Number

applicable Not nam Proper shipping e applicable Not Class applicable Not Subsidiary risk applicable Not Packing group applicable Not Labels applicable Not Hazchem Code applicable Not M BC RM C / (+) 13 precautions for user Special Rem arks ADR/RID, ADN, goods in the m eaning of Not dangerous IM DG -Code, ICAO/IATA -DGR inform ation Regulatory or specific for the substance regulations/legislation Safety, health and environm ental m ixture HSNO Approval Number HSR002647 Reagent Group Standard Kits Controls HSW required. handler certificate not Certified substance not required. Tracking hazardous Refer Regulations 2017, for further

Hazardous Ingredients

and Safety at W ork to the Health ation. inform following inventories: product are reported in the ponents of this The com AIIC inventory Not in com pliance with the DSL that are not following com ponents This product contains the NDSL. on the Canadian DSL nor Hum an serum / -plasm a / -hem olysate, liquid Glycols carboxylate M odified alkyl NZIoC inventory Not in com pliance with the ENCS inventory Not in com pliance with the ISHL inventory Not in com pliance with the KECI inventory Not in com pliance with the PICCS inventory Not in com pliance with the IECSC inventory Not in com pliance with the TCSI inventory Not in com pliance with the TSCA inventory. substance(s) not listed on TSCA Product

Contains

TECI inventory Not in com pliance with the ation Section 16: Other inform M BC RM C / (+) 14 Revision Date: 07.10.2024 form Date at dd.m .yy text other abbreviations Full of AIIC - Australian Inventory of Industrial Chem icals; ANTT - National Agency for Transport by Land of Brazil; ASTM - Am erican Society for the Testing of aterials; M bw - Body weight; CM R - Carcinogen, M utagen or Reproductive Toxicant; DIN - Standard of the Germ an Institute for Standardisation; DSL - Dom estic Substa (Canada); ECx nces List - associated with Concentration x% container to an

Response

ELx - Loading rate associated with x% Em S - Em ergency Schedule; ENCS - Existing and New Chem ical Substances (Japan); ErCx - Concentration associated with x% growth rate ; ERG - Em ergency Guide; GHS - Globally Harm onized System ; GLP - Good Laboratory Practice; IARC - International Agency for Research on Cancer; IATA - International Air Transport Association; IBC - International Code for the Construction and Equipm ent of Ships carying Dangerous Chem icals in Bulk; IC50 - Half m axim al inhibitory concentration; ICAO - International Civil Aviation Organization; IECSC - Inventory of Existing Chem ical Substances in China; IM DG - International aritim M e Dangerous Goods; IM O - International aritim M e Organization; ISHL - Industrial Safety and Health Law (Japan); ISO - International Organisation for Standardization; KECI - Korea Existing Chem icals Inventory; LC50 - Lethal Concentration to 50 % of a test population; LD50 - Leth al Dose to 50% of a test population (M edian Lethal Dose); M ARPOL - International Convention for the Prevention of Pollution from Ships; n.o.s. - Not Otherwise Specified; Nch - Chilean Norm ; NO(A)EC - No Observed (Adverse) Effect Concentration; NO(A)EL - No Observed (Adverse) Effect Level; NOELR - Observable Effect Loading Rate; NOErC No - based No Observed Effect Concentration on growth rate; NOEyC - No Observed Effect Concentration based on yield; NOM - Official M exican Norm ; NTP - National Toxicology Prog ram ; NZIoC - New Zealand Inventory of Chem icals; OECD - Organization for Econom ic Co -operation and Developm ent; OPTS - Office of Chem ical Safety and Pollution P302 + P352 of water. SKIN: W ash with plenty IF ON P333 + P313 ocurs: m edical skin iritation or rash Get If advice/ attention. P362 + P364 Take wash it before contam inated clothing and off reuse.

Prevention

PBT - Persistent, Bioacum ulative and Toxic substance; PICCS - Philippines Inventory of Chem icals and ical Chem Substances; (Q)SAR - (Quantitative) Structure Activity Relationship; REACH - Regulation (EC) No P261 breathing m ist or vapours. Avoid HIV -1-O RM C / O (+) 16 P272 allowed out of work clothing should not be Contam inated workplace. the P280 protective gloves. W ear

Hazard pictograms

word Signal W arning

Hazard statements

H317 reaction. M ay cause an allergic skin Precautionary

2.1 Classification of the substance or mixture

pictogram s : word Signal : W arning Hazard statem ents : H317 reaction. M ay cause an allergic skin Precautionary statem ents : Prevention : P261 breathing m ist or vapours. Avoid HIV -1-O RM C / O (+) 16 P272 allowed out of work clothing should not be Contam inated workplace. the P280 protective gloves. W ear Response : P302 + P352 of water. SKIN: W ash with plenty IF ON P333 + P313 ocurs: m edical skin iritation or rash Get If advice/ attention. P362 + P364 Take wash it before contam inated clothing and off reuse. Disposal : P501 approved waste Dispose of contents/ container to an disposal plant. result in classification hazards which do not Other None known. position Section 3: Com on ingredients /inform ation Substance / M ixture : M ixture Chem ical nature : potentially infectious. Handle as ponents Com Chem ical nam e CAS -No. Concentration (% w/w ) of: M ixture 5 -chloro -2-m ethyl -4-isothiazolin -3- 55965 -84 -9 >= 0.0025 - < 0.025 and 2 one -m ethyl -2H -isothiazol -3-one (3:1) Section 4: First -aid m easures General advice : dangerous area. M ove out of attendance. safety sheet to the doctor in Show this data victim unattended. Do not leave the If inhaled : M ove to fresh air. physician after significant exposure Consult a . seek m edical in recovery position and If unconscious,