Insulin (human), 28B-L-lysine-29B-L-proline-

Eli Lilly and Company

Revision date : 2005-02-15

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Health risk rating 1
Safety risk rating 1
Environmental risk rating 1

Note: Ingredients listed on restricted chemical lists

EC/CAS

56-81-5

Name of the chemical

glycerol

Concentration

N/A

EC/CAS

108-39-4

Name of the chemical

m-cresol

Concentration

N/A

EC/CAS

108-95-2

Name of the chemical

Phenol

Concentration

N/A

EC/CAS

1314-13-2

Name of the chemical

Zinc oxide; C.I. 77947

Concentration

N/A

EC/CAS

7732-18-5

Name of the chemical

Water, distilled, conductivity or of similar purity H2O

Concentration

N/A

General Information

Revision date

2005-02-15

Product name

Insulin (human), 28B-L-lysine-29B-L-proline-

Product Synonyms

Insulin, Lispro

Chemical name

Insulin (human), 28B-L-lysine-29B-L-proline-

Icons in SDS

Company Information

company name

Eli Lilly and Company

Section 2

SECTION 2: Hazards identification

Appearance: Clear solution Physical State: Liquid Odor: Odorless Emergency Overview Emergency Overview Effective Date: 10-Aug-1996 Lilly Laboratory Labeling Codes: Health 0 Fire 0 Reactivity 0 Primary Physical and Health Hazards: Not Considered a Health Hazard. Caution Statement: Insulin, Lispro is not considered to be a health hazard.

Principle Routes of Exposure

Inhalation and skin contact Effects of Overexposure: Dilute solutions do not pose a health hazard through typical routes of occupational exposure.

Medical Conditions Generally Aggravated by Exposure

Hypersensitivity to insulin Carcinogenicity: Insulin, lispro crystals - Not listed by IARC, NTP, ACGIH, or OSHA. One-year subcutaneous injection studies demonstrated no evidence of carcinogenicity in rats. Glycerin - Not listed by IARC, NTP, ACGIH, or OSHA. Two-year dietary studies demonstrated no evidence of carcinogenicity in rats. m-Cresol - Not listed by IARC, NTP, ACGIH, or OSHA. Two- to three-month dermal application studies with cresols demonstrated evidence of tumor promotion in mice. The relevance of these findings to humans is unknown. Remaining ingredients - Not listed by IARC, NTP, ACGIH, or OSHA.

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