General Information
Revision date
2011-01-04
Product name
Ontak
Product Synonyms
DAB389IL-2 Injection, IL-2 Fusion Toxin, IL-2 Fusion Protein, Ly335348 Injection
Chemical name
Denileukin Diftitox
CAS No.
173146-27-5
Icons in SDS
Company Information
company name
Eisai Inc
Section 2
SECTION 2: Hazards identification
DAB389IL-2 is a recombinant protein consisting of a portion of the diphtheria toxin molecule (fragments A and B) and human Interleukin-2. When dry, protein loses activity and is considered non-hazardous. The most commonly reported adverse effects seen in clinical trials were hypersensitivity reaction, loss of visual acuity, and vascular leak syndrome; effects have been delayed in onset and/or persistent Dose-limiting toxicities were moderate-to-severe nausea, vomiting, fever, chills, and/or persistent asthenia Potential Exposure Routes of Entry: Accidental injection or ingestion, eye or skin contact.
