DuPont R Thinners and Reducers

Potential health effects

Inhalation: May cause nose and throat irritation. May cause nervous system depression, characterized by the following progressive steps: headache, dizziness, nausea, staggering gait, confusion, unconsciousness. Reports have associated repeated and prolonged overexposure to solvents with permanent brain and nervous system damage. If this product contains or is mixed with an isocyanate activator/hardener, the following health effects may apply: Exposure to isocyanates may cause respiratory sensitization. This effect may be permanent. Symptoms include an asthma-like reaction with shortness of breath, wheezing, cough or permanent lung sensitization. This effect may be delayed for several hours after exposure. Repeated overexposure to isocyanates may cause a decrease in lung function, which may be permanent. Individuals with lung or breathing problems or prior reactions to isocyanates must not be exposed to vapors or spray mist of this product. Ingestion: May result in gastrointestinal distress. Skin or eye contact: May cause irritation or burning of the eyes. Repeated or prolonged liquid contact may cause skin irritation with discomfort and dermatitis. Other Potential Health Effects in addition to those listed above: 2,4-pentanedione 2,4-pentanedione, a component of this product, is regulated by the U.S. EPA, under a significant new use rule. It is a violation of federal law to sell or use this product in consumer applications, including to private individuals, schools, and vocational schools. Can be absorbed through the skin in harmful amounts. Repeated exposures to high concentrations has caused adverse health effects in laboratory animals. These effects involved the central nervous system, immune system, and the red blood cell forming system. No effect was seen at 100 ppm. The odor is disagreeable at a few ppm. Repeated or prolonged skin contact may cause any of the following: skin sensitization. Skin or eye contact may cause any of the following: irritation. Overexposure of this substance may cause effects on any of the following organs/systems: central nervous system, lungs, upper respiratory system, thymus. 4-chlorobenzotrifluoride Increased susceptibility to the effects of this material may be observed in people with preexisting disease of any of the following: skin. Prolonged or repeated exposure may cause damage to any of the following organs/systems: kidneys, liver, thyroid. Potential skin sensitizer that may cause allergic reactions and contact dermatitis resulting in severe irritation, dryness, and cracking of the skin. Ingestion may cause any of the following: gastrointestinal irritation. Eye contact may cause any of the following permanent eye injury. Inhalation may cause any of the following stupor (central nervous system depression), respiratory tract irritation Acetone The following medical conditions may be aggravated by exposure: lung disease, eye disorders, skin disorders. Overexposure may cause damage to any of the following organs/systems: blood, central nervous system, eyes, kidneys, liver, respiratory system, skin. Aliphatic hydrocarbon Laboratory studies with rats have shown that petroleum distillates can cause kidney damage and kidney or liver tumors. These effects were not seen in similar studies with guinea pigs, dogs, or monkeys. Several studies evaluating petroleum workers have not shown a significant increase of kidney damage or an increase in kidney or liver tumors. Aromatic hydrocarbon-A Laboratory studies with rats have shown that petroleum distillates can cause kidney damage and kidney or liver tumors. These effects were not seen in similar studies with guinea pigs, dogs, or monkeys. Several studies evaluating petroleum workers have not shown a significant increase of kidney damage or an increase in kidney or liver tumors. Aromatic hydrocarbon-B The following medical conditions may be aggravated by exposure: skin disorders. Laboratory studies with rats have shown that petroleum distillates can cause kidney damage and kidney or liver tumors. These effects were not seen in similar studies with guinea pigs, dogs, or monkeys. Several studies evaluating petroleum workers have not shown a significant increase of kidney damage or an increase in kidney or liver tumors. Butyl acetate May cause abnormal liver function. The following medical conditions may be aggravated by exposure: respiratory system. Tests for embryotoxic activity in animals has been inconclusive. Rats exposed to very high airborne levels have exhibited high frequency hearing deficits. The significance of this to man is unknown. Has been toxic to the fetus in laboratory animals at doses that are toxic to the mother. Cumene WARNING: This chemical is known to the State of California to cause cancer. Ethyl acetate Increased susceptibility to the effects of this material may be observed in people with preexisting disease of any of the following: eyes, respiratory system, skin. Tests in laboratory animals have shown effects on any of the following organs/systems: blood, kidneys, liver. Ethylbenzene Is an IARC NTP or