2-Hydroperfluoropropane Propane 1,1,1,2,3,3,3-Heptafluoro-

Potential health effects

Based on animal data, overexposure to HFC-227ea by inhalation may cause suffocation, if air is displaced by vapors, and irregular heart beat with a strange sensation in the chest, "heart thumping," apprehension, lightheadedness, feeling of fainting, dizziness, weakness, sometimes progressing to loss of consciousness and death. HFC-227ea may cause frostbite if liquid or escaping vapor contacts the skin. HFC-227ea may cause "frostbite-like" effects if the liquid or escaping vapors contact the eyes. In one study, human volunteers were selected to inhale HFC-227ea at a concentration of 6000 ppm but the study was terminated due to a rise in pulse rate that was believed to be unrelated to the chemical. In a subsequent study with human volunteers inhaling concentrations up to 8000 ppm no clinically significant effects were observed for any of the measured laboratory parameters. Individuals with preexisting diseases of the cardiovascular system or nervous system may have increased susceptibility from excessive exposures. Carcinogenicity Information None of the components present in this material at concentrations equal to or greater than 0.1% are listed by IARC, NTP, OSHA or ACGIH as a carcinogen. ----------------------------------------------------------------------