1,1,1,2,2,3,4,5,5,5-Decafluoropentane

Potential health effects

Gross overexposure by inhalation to HFC-43-10mee may cause suffocation if air is displaced by vapors and central nervous system stimulation with increased activity or sleeplessness, tremors or convulsions. These effects may be followed by central nervous system depression with dizziness, confusion, incoordination, drowsiness or unconsciousness. Based on data from other fluorocarbons, gross overexposure may be associated with irregular heartbeat or heart rhythm, which may produce heart palpitation, dizziness, weakness, unconsciousness and death. It is unlikely that concentrations sufficient to produce irregular heartbeat or heart rhythm would be achieved from HFC-43-10MEE without first producing other signs of toxicity. Immediate effects of overexposure to HFC-43-10mee by skin contact may include slight irritation with itching, redness or swelling. Repeated and/or prolonged exposure may cause defatting of the skin with itching, redness or rash. Based on animal data, significant skin permeation, and systemic toxicity after skin contact, appears unlikely. Immediate effects of overexposure to HFC-43-10mee by eye contact may include eye irritation with tearing, pain or blurred vision. The major ingestion hazard of HFC-43-10mee is aspiration (liquid entering the lungs during ingestion or vomiting) which may result in "chemical pneumonia." Symptoms include coughing, gasping, choking, shortness of breath, bluish discoloration of the skin, rapid breathing and heart rate, and fever. Pulmonary edema or bleeding, drowsiness, confusion, coma and seizures may occur in more serious cases. Symptoms may develop immediately or as late as 24 hours after exposure, depending on how much chemical entered the lungs. Increased susceptibility to the effects of HFC-43-10mee may be observed in persons with pre-existing disease of the central nervous system or the cardiovascular system. Carcinogenicity Information None of the components present in this material at concentrations equal to or greater than 0.1% are listed by IARC, NTP, OSHA or ACGIH as a carcinogen. ----------------------------------------------------------------------