Tretinoin

DSM Nutritional Products Ltd

Revision date : 2011-09-30

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GHS07 GHS09 GHS08
Health risk rating 5
Safety risk rating 1
Environmental risk rating 4

Note: Ingredients listed on restricted chemical lists

EC/CAS

206-129-0/302-79-4

Name of the chemical

Tretinoin (INN) (retinoic acid and its salts)

Concentration

>= 97,5

General Information

Version

1.2

Revision date

2011-09-30

Product name

Tretinoin

Substance name

2,4,6,8-Nonatetraenoic acid, 3,7-dimethyl-9-(2,6,6-trimethyl-1- cyclohexen-1-yl)-, (all-E)-

CAS No.

302-79-4

1.2.1 Relevant identified uses

Ingredient for pharmaceutical products

Emergency telephone

+41 62 866 2314

Icons in SDS

GHS07 GHS08 GHS09 M004 M009 M010 M011 M017

Company Information

company name

DSM Nutritional Products Ltd

e-mail address of the competent person responsible for the Safety Data Sheet

sds.nutritionalproducts@dsm.com

GHS Information

Signal word

Danger

Hazard Codes

Hazard statements (CLP)

H315, H319, H335, H360D, H411

Hazard statements

Code

Statements

H315

Causes skin irritation

Section 2

SECTION 2: Hazards identification

Regulation (EC) No. 1272/2008 Classification of the substance or mixture

Signal word

Danger

Hazard statements

H315 Causes skin irritation. H319 Causes serious eye irritation. H335 May cause respiratory irritation. H360D May damage the unborn child. H411 Toxic to aquatic life with long lasting effects.

Prevention

P201 Obtain special instructions before use. P273 Avoid release to the environment. P280 Wear protective gloves/ eye protection/ face protection.

Response

P302 + P352 IF ON SKIN: Wash with plenty of soap and water. P304 + P340 IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P308 + P313 IF exposed or concerned: Get medical advice/ attention.

Hazardous Ingredients

302-79-4 tretinoin

2.3 Other hazards

Risk of dust explosion. Women of childbearing age must avoid any overexposure.

2.1 Classification of the substance or mixture

Classification (REGULATION (EC) No 1272/2008) Skin irritation, Category 2 H315: Causes skin irritation. Eye irritation, Category 2 H319: Causes serious eye irritation. Specific target organ toxicity - single H335: May cause respiratory irritation. exposure, Category 3 Chronic aquatic toxicity, Category 2 H411: Toxic to aquatic life with long lasting effects. Reproductive toxicity, Category 1A H360D: May damage the unborn child. Classification (67/548/EEC, 1999/45/EC) Toxic to Reproduction Category 1 R61: May cause harm to the unborn child. Irritant R36/37/38: Irritating to eyes, respiratory system and skin. Dangerous for the environment R51/53: Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.

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