DOWTHERM 4000 Heat Transfer Fluid, Dyed

SECTION 2: Hazards identification

Emergency Overview Appearance Physical state Liquid. Color Orange Odor Characteristic ® ™ Trademark of The Dow Chemical Company ("Dow") or an affiliated Hazard Summary WARNING!! Harmful or fatal if swallowed. May cause eye irritation. Isolate area.

Potential health effects

Eyes: May cause slight eye irritation. Corneal injury is unlikely. Vapor or mist may cause eye irritation. Skin: Brief contact is essentially nonirritating to skin. Prolonged contact may cause slight skin irritation with local redness. Repeated contact may cause skin irritation with local redness. Prolonged skin contact is unlikely to result in absorption of harmful amounts. Repeated skin exposure to large quantities may result in absorption of harmful amounts. Massive contact with damaged skin or of material sufficiently hot to burn skin may result in absorption of potentially lethal amounts. Inhalation: At room temperature, exposure to vapor is minimal due to low volatility. With good ventilation, single exposure is not expected to cause adverse effects. If material is heated or areas are poorly ventilated, vapor/mist may accumulate and cause respiratory irritation and symptoms such as headache and nausea. Ingestion: Oral toxicity is expected to be moderate in humans due to ethylene glycol even though tests with animals show a lower degree of toxicity. Ingestion of quantities (approximately 65 mL (2 oz.) for diethylene glycol or 100 mL (3 oz.) for ethylene glycol) has caused death in humans. May cause nausea and vomiting. May cause abdominal discomfort or diarrhea. Excessive exposure may cause central nervous system effects, cardiopulmonary effects (metabolic acidosis), and kidney failure. Chronic Exposure: For the major component(s): Observations in humans include: Nystagmus (involuntary eye movement). In animals, effects have been reported on the following organs: Kidney. Liver. Based on animal studies, ingestion of very large amounts of ethylene glycol appears to be the major and possibly only route of exposure to produce birth defects. Exposures by inhalation or skin contact, the primary routes of occupational exposure, had minimal effect on the fetus, in animal studies. In laboratory animals, boron compounds have caused birth defects only at doses toxic to the mother and have been toxic to the fetus at doses nontoxic to the mother. Ingestion of large amounts of ethylene glycol has been shown to interfere with reproduction in animals. In animal studies, boron compounds have been shown to interfere with fertility in males, and to a lesser degree in females.