MEVINPHOS 150 EC

SECTION 2: Hazards identification

Toxicity class: WHO Ia; EPA I ADI 0.0015 mg/kg NOEL 4 mg/kg (rats) - 2 year 5 mg/kg diet (dogs) - 2 year Main Hazard: SUBJECT: MEVINPHOS 150 EC DOCUMENT NO: PS 057 Revision Date: JANUARY 1998 Revision Date: NOVEMBER 1999 REVISION NO: 1 PAGE : 1 of 6 PRODUCT CODE: - This compound inhibits cholinesterase enzyme activity in the nervous tissue. It is very toxic. Contact with skin, inhalation of spray, or swallowing may be fatal. Fire and explosion hazard: Product is flammable and explosive due to the solvent. Chemical Hazard: None known. Biological Hazard:

Principle Routes of Exposure

Skin and eye contact, ingestion and inhalation. Ingestion: Highly toxic by ingestion. See point 4 symptoms. Inhalation: Highly toxic by inhalation depends on volatility of compound. See point 4 for symptoms. Skin contact: Highly toxic, due to possible absorption. Irritating to skin. Eye contact: Highly toxic. Irritating to eyes Carcinogenicity: See section 11. Mutagenicity: See section 11. Neurotoxicity: See section 11. Reproductive /Teragenicity: See section 11. 2. FIRST AID MEASURES AND PRECAUTIONS Symptoms of exposure to the product include: nausea, headache, tiredness, giddiness, blurred vision and pupillary constriction. Depending on severity of poisoning these symptoms become worse with the onset of vomiting, abdominal pain, diarrhea, sweating and salivation. Confusion, ataxia, slurred speech, loss of reflexes are some of the central nervous system effects that may lead to misdiagnosis of acute alcoholism. OVEREXPOSURE EFFECTS: After inhalation of vapours or aerosols effects appear within minutes: ocular and respiratory effects generally appear first. These include marked meiosis, ocular pain, conjunctival congestion, diminished vision, ciliary spasm and brow ache. With acute systemic absorption, meiosis may not be evident due to systemic absorption, meiosis may not be evident due to sympathetic discharge in response to the hypertension. In addition to rhinorrhea and hyperemia of the upper respiratory tract, respiratory effects consist of “tightness” in the chest and wheezing respiration caused by the combination of bronchoconstriction and increased bronchial secretion. Gastrointestinal symptoms occur earliest after ingestion and include anorexia, nausea and vomiting, abdominal cramps, and diarrhea. With percutaneous absorption of liquid, localized sweating and muscular fasciculation in the immediate vicinity are generally the earliest manifestations. Severe intoxication is manifested by extreme salivation, involuntary defecation and urination, sweating, lacrimation, penile erection, bradycardia and hypotentsion. The airway should be kept clear to maintain respiration, particularly when the patient is unconsious or has vomited. The mouth and pharynx should be cleared and denatures removed. The jaw should be supported and the patient placed in a face down position with the head down and turned to one side, with the tongue drawn forward. First aid should include, if necessary, mouth-to-nose respiration, cardiac massage and avoidance of injury in patients with trauma. Inhalation: Remove source of contamination or move victim to fresh air. Keep affected person warm and at rest. Supply oxygen if necessary. Treat symptomatically and supportively. Seek medical advice immediately.