Piperzine 53%

SECTION 2: Hazards identification

Adverse Effects Adverse effects may include dizziness, drowsiness, muscle weakness, tremors, abdominal cramps or pain, diarrhea, nausea, vomiting, and headache. Possible allergic reaction to material if inhaled, ingested or in contact with skin. Overdose Effects Overdose effects may include muscle weakness of the extremities, difficulty breathing, and seizures. Acute Possible eye, skin, gastrointestinal and/or respiratory tract irritation. Chronic Possible hypersensitization. Inhalation May cause irritation. Avoid inhalation. Remove to fresh air. Eye May cause irritation. Flush with copious quantities of water. Skin May cause irritation. Prolonged or repeated contact may cause sensitization. Flush with copious Quantities of water. Ingestion May cause irritation. Flush out mouth with water. This material is rapidly absorbed from the gastrointestinal tract.

Medical Conditions Generally Aggravated by Exposure

Hypersensitivity to the material, seizure disorders, and impaired liver or kidney function. Cross Sensitivity Although rare, persons who have been sensitized to ethylenediamine (a substance used as a stabilizer in topical creams), could experience a life-threatening contact allergy when exposed to piperazine. Pregnancy Comments Adequate and well-controlled pregnancy studies in humans have not been done. Some animal studies have shown no evidence that piperazine causes birth defects, although it has also been reported that it does cause birth defects in rabbits. There have been isolated reports of fetal malformations following clinical use in humans, but no causal relationship has been established.