Homocystein (Liquid)

SECTION 2: Hazards identification

OSHA persists. Ingestion: Get medical aid. Wash mouth out with Reagent R1 1,2-Propanediol 10% 57-55-6 200-338-0 water. None Listed None Listed 24/25 Inhalation: Remove from exposure and move to fresh Reagent R2 Glycerol 20% 56-81-5 200-289-5 None air immediately. If not breathing, give artificial Listed None Listed 24/25 respiration. If breathing is difficult, give oxygen. Get Reagent R3 Glycerol 15% 56-81-5 200-289-5 None medical aid. Listed None Listed 24/25 Notes to Physician: Treat symptomatically and NOTE: Physical and health hazard information on supportively. reagent mixtures has not been determined. Any physical and health information noted is based on 1) evaluation of data for the pure ingredients, and 2) concentration of ingredients as packaged 5. FIRE-FIGHTING MEASURES 8. EXPOSURE CONTROLS / PERSONNEL PROTECTION 1,2-PROPANEDIOL & GLYCEROL: 1,2-PROPANEDIOL: General Information: As in any fire, wear a self- Engineering Controls: contained breathing apparatus in pressure-demand, Use adequate general or local exhaust ventilation to MSHA/NIOSH (approved or equivalent), and full keep airborne concentrations below the permissible protective gear. exposure limits. Extinguishing Media: Use water spray, dry chemical, Exposure Limits carbon dioxide, or chemical foam. United Kingdom, WEL - TWA: 150 ppm TWA (total particulate and vapour); 474 mg/m3 6. ACCIDENTAL RELEASE MEASURES TWA (total particulate); 1,2-PROPANEDIOL: United Kingdom, WEL - STEL: 450 ppm STEL (total General Information: Use proper personal protective particulate and vapour); 1422 mg/m3 equipment as indicated in Section 8. STEL (total particulate) Spills/Leaks: Absorb spill with inert material (e.g. Personal Protective Equipment vermiculite, sand or earth), then place in suitable Eyes: Wear chemical splash goggles. container. Skin: Wear appropriate protective gloves to prevent GLYCEROL: skin exposure. General Information: Use proper personal protective Clothing: Wear appropriate protective clothing to equipment as indicated in Section 8. Spills/Leaks: prevent skin exposure. Absorb spill with inert material (e.g. vermiculite, Respirators: Follow the OSHA respirator regulations sand or earth), then place in suitable container. Do found in 29 CFR 1910.134 or European Standard EN not let this chemical enter the environment. 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if 7. HANDLING AND STORAGE irritation or other symptoms are experienced. 1,2-PROPANEDIOL: GLYCEROL: Handling: Wash thoroughly after handling. Use with Engineering Controls: adequate ventilation. Avoid breathing dust, vapor, mist, Use adequate ventilation to keep airborne or gas. Avoid contact with skin and eyes. concentrations low. Exposure Limits

Storage

Keep away from sources of ignition. Store in a United Kingdom, WEL - TWA: 10 mg/m3 cool, dry place. Store in a tightly closed container. TWA (mist) United Kingdom, GLYCEROL: WEL - STEL: 30 mg/m3 Handling: Avoid breathing dust, vapor, mist, or gas. STEL (mist); United States OSHA: 15 mg/m3 Avoid contact with skin and eyes. Avoid ingestion and TWA (total dust); 5 mg/m3 inhalation. TWA (respirable Store in a cool, dry place. Store in a tightly fraction); Belgium - TWA: 10 mg/m3 closed container. VLE (mist); France - VME: 10 mg/m3 VME; Malaysia: 10 mg/m3 TWA (mist); Netherlands: 10 mg/m3 MAC (mist); Spain: 10 mg/m3 VLA-ED Personal Protective Equipment Eyes: Wear chemical splash goggles. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations 10. STABILITY AND REACTIVITY found in 29 CFR 1910.134 or European Standard EN 1,2-PROPANEDIOL: 149. Use a NIOSH/MSHA or European Standard EN 149 Chemical Stability: Stable under normal temperatures approved respirator if exposure limits are exceeded or if and pressures. Hygroscopic: irritation or other symptoms are experienced. absorbs moisture or water from the air. 9. PHYSICAL AND CHEMICAL PROPERTIES Conditions to Avoid: Incompatible materials, exposure 1,2-PROPANEDIOL to moist air or water. Physical State: Viscous liquid Incompatibilities with Other Materials: Oxidizing Color: Clear agents, reducing Odor: odorless agents, acid chlorides, nitric acid, pH: Not available acid anhydrides, hydrofluoric Vapor Pressure: 0.13mbar @20 deg C acid, chloroformates. Viscosity: 45 mPas @20 deg C Hazardous Decomposition Products: Carbon monoxide, Boiling Point: 187 deg C @760mmHg ( 368.60°F) carbon dioxide. Freezing/Melting Point: -60 deg C ( -76.00°F) Hazardous Polymerization: Will not occur Autoignition Temperature: 400 deg C ( 752.00 deg F) GLYCEROL: Flash Point: 99 deg C ( 210.20 deg F) Chemical Stability: Stable under normal temperatures Explosion Limits Lower 2.5 Vol % and pressures. Hygroscopic: Explosion Limits Upper 12.6 Vol % absorbs moisture or water from Decomposition Temperature: Not available the air. Solubility in water: Miscible Conditions to Avoid: Incompatible materials, exposure Specific Gravity/Density: 1.030 to moist air or water, temperatures above 140°C. Molecular Formula: C3H8O2 Incompatibilities with Other Materials: Strong oxidizing Molecular Weight: 76.09 agents, lead GLYCEROL: oxide, nitric acid, sulfuric acid, Physical State: Viscous liquid hydrogen peroxide, potassium Color: clear, colorless permanganate, calcium hypochlorite, perchloric acid. Odor: odorless Hazardous Decomposition Products: Carbon monoxide, pH: 5 (100 g/l aq.sol.) carbon dioxide. Vapor Pressure: 0.003mbar @50 deg C Hazardous Polymerization: Will not occur. Viscosity: 1069 mPas @20 deg C Boiling Point: 290 deg C @760mmHg ( 554.00°F)

TOXICOLOGICAL INFORMATION

Freezing/Melting Point: 18 deg C ( 64.40°F) 1,2-PROPANEDIOL RTECS# CAS# 57-55-6 TY2000000 Autoignition Temperature: 400 deg C ( 752.00 deg F) LD50/LC50 RTECS CAS# 57-55-6 Draize test, rabbit, Flash Point: 160 deg C ( 320.00 deg F) eye 100 mg Mild; Draize test, rabbit, eye 500 mg/24H Explosion Limits Lower 0.9 Vol % Mild; Oral, mouse: LD50 = 22 gm/kg; Explosion Limits Upper Not available Oral, mouse: LD50 = 20300 mg/kg; Decomposition Temperature: Not available Oral, rabbit: LD50 = 18500 mg/kg; Solubility in water: >500 g/l (20°C) Oral, rat: LD50 = 20 gm/kg; Specific Gravity/Density: 1.261 Skin, rabbit: LD50 = 20800 mg/kg; Molecular Formula: C3H8O3 Skin, rabbit: LD50 = 20800 mg/kg; Molecular Weight: 92.09 Carcinogenicity: 1,2-Propanediol - Not listed as a carcinogen by ACGIH, IARC, NTP, or CA Prop 65. Other: See actual entry in RTECS for complete TSCA information. CAS# 56-81-5 is listed on the TSCA Inventory The toxicological properties have not been fully investigated.

Further information

The information herein is believed to be correct as of 12. ECOLOGICAL INFORMATION the date hereof but is provided without warranty of any kind. The recipient of our 1,2-PROPANEDIOL Ecotoxicity Fish Fathead Minnow products is responsible for observing any laws and LC50 54900 mg/L; 96h; Fish Rainbow trout LC50 guidelines applicable 51600 mg/L; 96h; Daphnia Daphnia EC50 34400 mg/L; 48h Other: Readily biodegradable