Isovue 128, 200, 250, 300, 370 solutions

SECTION 2: Hazards identification

COMPONENTS HAZARDOUS CONCENTRATION CAS EXPOSURE (> 1%) (Y/N) (w/w%)(w/v%) NUMBER GUIDELINE Iopamidol N 23-54 26-76 60166-93-0 none Water N > 1 7732-18-5 none Components present at < 1% or used for pH adjustment: tromethamine, edetate calcium disodium, hydrochloric acid, sodium hydroxide. SECTION 3: HEALTH HAZARDS IDENTIFICATION Effects of Overexposure Routes of Entry: 1. Inhalation: Under normal conditions, exposure to this material by inhalation is not expected to occur. However, in a situation where the liquid would be aerosolized, there may be potential for inhalation. The extent of systemic absorption of the material after inhalation is not known. 2. Skin Contact: Exposure may occur via skin contact if gloves and protective clothing are not worn. The extent of systemic absorption of the material after skin contact is not known. 3. Ingestion: Ingestion of large quantities of this material in an occupational setting would not be expected to occur. Ingestion of trace amounts of the material might occur if the material contacts hands and hands are not washed prior to eating, drinking or smoking. The extent of systemic absorption of the material after ingestion is not known. Acute 1. Ingestion: Inadvertent ingestion of trace amounts of this material would not be expected to result in symptoms. 2. Inhalation: Inhaling small doses of aerosolized material would not be expected to result in symptoms. 3. Skin Contact: a. Toxic: Contact with small quantities of material for short periods is not expected to result in pharmacologic or toxic effects. b. Irritation: Material contains low concentrations of components that are mild irritants or possible irritants. It may have potential to cause mild irritation, however, moderate or severe irritation is not expected. c. Sensitization: This material may act as a sensitizer (allergen) for those persons who are allergic to these formulations, iodides, or other components in the formulation. 4. Eye Contact: No information. Chronic Repeated and prolonged exposure to skin may cause skin irritation. Exposure Guideline Summary: An exposure guideline has not been established for this material. Carcinogen Lists IARC: No NTP: No OSHA: No Target Organs: None known. Medical Condition Aggravated by Exposure: Sensitivity to iodine.