Ürün Adi

SECTION 2: Hazards identification

1272/2008 Specific M-Factor registration Index No) according to concentration (long-term) number Regulation limit (SCL) (EC) No.

Hazard statements

see section 16 Acute Toxicity Estimate No information available Chemical name Oral LD50 mg/kg Dermal LD50 mg/kg Inhalation LC50 - 4 Inhalation LC50 - 4 Inhalation LC50 - 4 hour - dust/mist - hour - vapor - mg/L hour - gas - ppm mg/L HEPES 2000 No data available 7365-45-9 This product does not contain candidate substances of very high concern at a concentration >=0.1% (Regulation (EC) No.

Storage

Conditions Keep container tightly closed in a dry and well-ventilated place. 7.3. Specific end use(s) Risk Yönetim Yöntemleri (RMM) Gerekli bilgi bu Güvenlik Bilgi Formunda yer almaktadir. SECTION 8: Exposure controls/personal protection 8.1. Control parameters Exposure Limits This product, as supplied, does not contain any hazardous materials with occupational exposure limits established by the region specific regulatory bodies. Biological occupational exposure This product, as supplied, does not contain any hazardous materials with biological limits limits established by the region specific regulatory bodies. Derived No Effect Level (DNEL) - Workers No information available Derived No Effect Level (DNEL) - General Public No information available. Predicted No Effect Concentration (PNEC) No information available. 8.2. Exposure controls Engineering controls No information available. Kisisel koruyucu ekipman Eye/face protection Appropriate eye/face protection should be selected and used according to the chemical nature, hazards and use of this product and safety requirements of the local jurisdiction. Hand protection Appropriate hand protection should be selected and used according to the chemical nature, hazards and use of this product and safety requirements of the local jurisdiction. Skin and body protection Appropriate skin and body protection should be selected and used according to the chemical nature, hazards and use of this product and safety requirements of the local jurisdiction. Respiratory protection Appropriate respiratory protection should be selected and used according to the chemical nature, hazards and use of this product and safety requirements of the local jurisdiction. If exposure limits are exceeded or irritation is experienced, ventilation and evacuation may be required. General hygiene considerations Handle in accordance with good industrial hygiene and safety practice. Environmental exposure controls No information available. BÖLÜM 9: Fiziksel ve kimyasal özellikler 9.1. Information on basic physical and chemical properties Physical state Solid Görünüm Lyophilized Renk Off-white to white Koku Bilgi mevcut değil. Koku esigi Bilgi mevcut değil Property Values

Remarks

Method Melting point / freezing point No data available Hiçbiri bilinmiyor Initial boiling point and boiling No data available Hiçbiri bilinmiyor range Alevlenebilirlik No data available Hiçbiri bilinmiyor Flammability Limit in Air Hiçbiri bilinmiyor Upper flammability or explosive No data available limits Lower flammability or explosive No data available limits Parlama noktasi No data available Hiçbiri bilinmiyor Kendiliginden tutusma sicakligi No data available Hiçbiri bilinmiyor Bozunma sicakligi Hiçbiri bilinmiyor pH No data available Uygulanamaz pH (sulu çözelti olarak) No data available None known Kinematik viskozite No data available Hiçbiri bilinmiyor Dinamik viskozite No data available Hiçbiri bilinmiyor Water solubility No data available Hiçbiri bilinmiyor Çözünürlük(ler) No data available Hiçbiri bilinmiyor Bölüntü katsayisi No data available Hiçbiri bilinmiyor Buhar basinci No data available Hiçbiri bilinmiyor Bagil yogunluk No data available Uygulanamaz Yigin yogunlugu No data available Liquid Density mevcut veri yok Relative vapor density No data available Hiçbiri bilinmiyor Particle characteristics Particle Size Bilgi mevcut değil Particle Size Distribution Bilgi mevcut değil

Further information

9.2.1. Information with regard to physical hazard classes Uygulanamaz 9.2.2. Other safety characteristics Bilgi mevcut değil BÖLÜM 10: Kararlilik ve tepkime 10.1. Reactivity Reactivity No information available. 10.2. Chemical stability Stability Stable under normal conditions. Patlama verileri Sensitivity to mechanical impact None. Sensitivity to static discharge None. 10.3. Possibility of hazardous reactions Possibility of hazardous reactions None under normal processing. 10.4. Conditions to avoid Conditions to avoid None known based on information supplied. 10.5. Incompatible materials Incompatible materials None known based on information supplied. 10.6. Hazardous decomposition products Hazardous decomposition products Edinilen bilgilere göre bilinen yok. BÖLÜM 11: Toksikolojik bilgiler 11.1. Information on hazard classes as defined in Regulation (EC) No 1272/2008 Information on likely routes of exposure Product Information Inhalation Specific test data for the substance or mixture is not available. Eye contact Specific test data for the substance or mixture is not available. Skin contact Specific test data for the substance or mixture is not available. Ingestion Specific test data for the substance or mixture is not available. Symptoms related to the physical, chemical and toxicological characteristics Symptoms No information available. Acute toxicity Numerical measures of toxicity No information available The following values are calculated based on chapter 3.1 of the GHS document ATEmix (oral) 7,369.00 mg/kg ATEmix (dermal) 7,369.00 mg/kg 0 % of the mixture consists of ingredient(s) of unknown acute oral toxicity. 0 % of the mixture consists of ingredient(s) of unknown acute dermal toxicity. 0 % of the mixture consists of ingredient(s) of unknown acute inhalation toxicity (gas). 0 % of the mixture consists of ingredient(s) of unknown acute inhalation toxicity (vapor). 0 % of the mixture consists of ingredient(s) of unknown acute inhalation toxicity (dust/mist). Chemical name Oral LD50 Dermal LD50 Inhalation LC50 HEPES > 2000 mg/kg ( Rat ) - Kisa ve uzun süreli maruz kalinmasindan kaynaklanan kronik etkilerin yani sira gecikmeli ve anlik etkiler Skin corrosion/irritation No information available. Serious eye damage/eye irritation No information available. Respiratory or skin sensitization No information available. Germ cell mutagenicity No information available. Carcinogenicity No information available. Reproductive toxicity No information available. STOT - single exposure No information available. STOT - repeated exposure No information available. Aspiration hazard No information available. 11.2. Information on other hazards 11.2.1. Endocrine disrupting properties Endocrine disrupting properties No information available. 11.2.2. Other information Diger advers etkiler Bilgi mevcut değil. BÖLÜM 12: Ekolojik bilgiler 12.1. Toxicity Ecotoxicity The environmental impact of this product has not been fully investigated. Unknown aquatic toxicity Contains 72.86 % of components with unknown hazards to the aquatic environment. Chemical name Algae/aquatic plants Fish Toxicity to Crustacea microorganisms HEPES - LC50: >100mg/L (96h, - Danio rerio) 12.2. Persistence and degradability Kalicilik ve bozunabilirlik Bilgi mevcut değil. 12.3. Bioaccumulative potential Bioaccumulation There is no data for this product. Chemical name Partition coefficient HEPES <-3.85 12.4. Mobility in soil Topraktaki hareketlilik Bilgi mevcut değil. 12.5. Results of PBT and vPvB assessment PBT and vPvB assessment The product does not contain any substance(s) classified as PBT or vPvB above the threshold of declaration. Chemical name PBT and vPvB assessment HEPES The substance is not PBT / vPvB 12.6. Endocrine disrupting properties Endocrine disrupting properties No information available. 12.7. Other adverse effects Bilgi mevcut değil. SECTION 13: Disposal considerations 13.1. Waste treatment methods Waste from residues/unused Dispose of in accordance with local regulations. Dispose of waste in accordance with products environmental legislation. Contaminated packaging Do not reuse empty containers. BÖLÜM 14: Tasimacilik bilgileri IATA 14.1 UN number or ID number Not regulated 14.2 14.3 Transport hazard class(es) Not regulated 14.4 Ambalajlama grubu Düzenlenmemistir 14.5 Çevresel zararliliklar Uygulanamaz 14.6 Special precautions for user Özel Hükümler Hiçbiri IMDG 14.1 UN number or ID number Not regulated 14.2 14.3 Transport hazard class(es) Düzenlenmemistir 14.4 Ambalajlama grubu Düzenlenmemistir 14.5 Çevresel zararliliklar Uygulanamaz 14.6 Special precautions for user Özel Hükümler Hiçbiri 14.7 Maritime transport in bulk Bilgi mevcut değil according to IMO instruments RID 14.1 UN number or ID number Düzenlenmemistir 14.2 14.3 Transport hazard class(es) Düzenlenmemistir 14.4 Ambalajlama grubu Düzenlenmemistir 14.5 Çevresel zararliliklar Uygulanamaz 14.6 Special precautions for user Özel Hükümler Hiçbiri ADR 14.1 UN number or ID number Düzenlenmemistir 14.2 14.3 Transport hazard class(es) Düzenlenmemistir 14.4 Ambalajlama grubu Düzenlenmemistir 14.5 Çevresel zararliliklar Uygulanamaz 14.6 Special precautions for user Özel Hükümler Hiçbiri BÖLÜM 15: Mevzuat bilgileri 15.1. Safety, health and environmental regulations/legislation specific for the substance or mixture Avrupa Birligi Take note of Directive 98/24/EC on the protection of the health and safety of workers from the risks related to chemical agents at work. Authorizations and/or restrictions on use: This product does not contain substances subject to authorization (Regulation (EC) No. 1907/2006 (REACH), Annex XIV) This product does not contain substances subject to restriction (Regulation (EC) No. 1907/2006 (REACH), Annex XVII) Persistent Organic Pollutants Not applicable Ozone-depleting substances (ODS) regulation (EC) 1005/2009 Not applicable Uluslararasi Envanterler TSCA Contact supplier for inventory compliance status DSL/NDSL Contact supplier for inventory compliance status EINECS/ELINCS Contact supplier for inventory compliance status ENCS Contact supplier for inventory compliance status IECSC Düzenlenmis KECL Contact supplier for inventory compliance status PICCS Contact supplier for inventory compliance status AIIC Contact supplier for inventory compliance status NZIoC Contact supplier for inventory compliance status Döküm: TSCA - Amerika Birlesik Devletleri Toksik Maddeler Kontrol Yasasi Bölüm 8(b) Envanteri DSL/NDSL - Kanada Yerli Maddeler Listesi/Yerli Olmayan Maddeler Listesi EINECS/ELINCS - Avrupa Mevcut Kimyasal Maddeler Envanteri/Avrupa Onayli Kimyasal Maddeler Listesi ENCS - Japonya Mevcut ve Yeni Kimyasal Maddeler IECSC - Çin Mevcut Kimyasal Maddeler Envanteri KECL - Kore Mevcut ve Degerlendirilmis Kimyasal Maddeler PICCS - Filipinler Kimyasallar ve Kimyasal Maddeler Envanteri AICS - Avustralya Kimyasal Maddeler Envanteri NZIoC - Yeni Zelanda Kimyasallar Envanteri 15.2. Chemical safety assessment Kimyasal Güvenlik Raporu Bilgi mevcut değil BÖLÜM 16: Diger bilgiler Güvenlik bilgi formunda kullanilan kisaltmalar için gösterge veya açiklama Döküm SVHC: Substances of Very High Concern for Authorization: PBT: Persistent, Bioaccumulative, and Toxic (PBT) Substances vPvB: Very Persistent and very Bioaccumulative (vPvB) Substances STOT: Specific Target Organ Toxicity ATE: Acute Toxicity Estimate LC50: 50% Lethal Concentration LD50: 50% Lethal Dose