N-METHYL-2-PYRROLIDONE DIPROPYLENE GLYCOL MONOMETHYL ETHER

Hazard statements (CLP)

H225, H226, H302, H304, H315, H318, H319, H332, H335, H336, H360D, H373, H400, H410, H411

Code

Statements

H225

Highly Flammable liquid and vapour

SECTION 2: Hazards identification

The product is classified as hazardous pursuant to the provisions set forth in EC Regulation 1272/2008 (CLP) CAS 1-METHOXY-2-PROPANOL Workers exposed to this chemical agent must not undergo health checks, provided that available risk-assessment When exposed to the air it oxidates slowly to develop hydroperoxides. Completely mixable with water with a WEL ETHYLBENZENE 100-41-4 GBR Avoid release to the environment. 2,5 ≤ x < 3 220 50 Flam. Liq. 2 H225, Acute Tox. 4 H332, Asp. Tox. 1 H304, 441 100 The emissions generated by manufacturing processes, including those generated by ventilation equipment, should - IATA DGR: International Air Transport Association Dangerous Goods Regulation from improper uses. P273 TLV XYLENE (MIXTURE OF ISOMERS) BGR GRC 435 360 100 1080 545 300 SKIN SUITABLE EXTINGUISHING EQUIPMENT N-METHYL-2-PYRROLIDONE STOT - REPEATED EXPOSURE Solubility in water BUTANOL data prove that the risks related to the workers' health and safety are modest and that the 98/24/EC directive is neutral or slightly basic reaction. It does not attack common materials. TLV LD50 (Oral) GRC Do NOT induce vomiting. 435 100 STOT RE 2 H373 1000 - 10000 mg/l 3500 mg/kg Rat 650 150 Keep away from heat, sparks and naked flames; do not smoke or use matches or lighters. Vapours may catch fire be checked to ensure compliance with environmental standards. - IC50: Immobilization Concentration 50% Provide appointed staff with adequate training on how to use chemical products. P331 TLV NDS Toxic effect on the central nervous system (encephalopathy); irritating for the skin, conjunctiva, cornea and CZE POL 200 180 500 360 SKIN

2.1 Classification of the substance or mixture

EC Extinguishing substances are: carbon dioxide, foam, chemical powder. For product loss or leakage that has not Rapidly degradable Partition coefficient: soil/water ADR / RID: respected. P301+P310 NDS Incompatible with: sulphur,carbon disulphide,oxidising substances,aluminium,metals.Incompatible materials: LD50 (Dermal) 202-849-4 POL Environmentally Hazardous IF SWALLOWED: Immediately call a POISON CENTER / doctor / . . . 100 0,388 15354 mg/kg Rabbit and an explosion may occur; vapour accumulation is therefore to be avoided by leaving windows and doors open Product residues must not be indiscriminately disposed of with waste water or by dumping in waterways. - IMDG: International Maritime Code for dangerous goods INDEX caught fire, water spray can be used to disperse flammable vapours and protect those trying to stem the leak. 1-METHOXY-2-PROPANOL May cause damage to organs VLEP OEL natural rubbers,plastic materials. respiratory apparatus. LC50 (Inhalation) 601-023-00-4 FRA EU 88,4 375 100 20 17,2 mg/l/4h Rat 442 568 100 150 SKIN and ensuring good cross ventilation. Without adequate ventilation, vapours may accumulate at ground level and, if - IMO: International Maritime Organization P101 OEL WEL TLV-ACGIH EU GBR If medical advice is needed, have product container or label at hand. 221 441 184 100 50 442 552 368 100 125 100 SKIN

Results of PBT and vPvB assessment

The product is classified as hazardous pursuant to the provisions set forth in (EC) Regulation 1272/2008 (CLP) BUTANOL UNSUITABLE EXTINGUISHING EQUIPMENT ETHYL ACETATE The product is classified as hazardous pursuant to the provisions set forth in (EC) Regulation 1272/2008 (CLP) VOC (Directive 2004/42/EC) : Dissolves various plastic materials.Stable in normal conditions of use and storage. ignited, catch fire even at a distance, with the danger of backfire. Avoid bunching of electrostatic charges. When - INDEX NUMBER: Identifier in Annex VI of CLP Changes to previous review: P102 TLV-ACGIH TLV ETHYLBENZENE GRC Keep out of reach of children. 434 435 100 651 545 150 125 (and subsequent amendments and supplements). The product thus requires a safety datasheet that complies with CAS Do not use jets of water. Water is not effective for putting out fires but can be used to cool containers exposed to 1-METHOXY-2-PROPANOL

Aspiration hazard

Solubility in water IMDG: Two-pack performance coatings. (and subsequent amendments and supplements). The product thus requires a safety datasheet that complies with BUTANOL As the counterparts of benzene, may have an acute effect on the central nervous system, with depression, 71-36-3 Marine Pollutant 1,5 ≤ x < 2 Flam. Liq. 3 H226, Acute Tox. 4 H302, Eye Dam. 1 H318, > 10000 mg/l SECTION 9. Physical and chemical properties performing transfer operations involving large containers, connect to an earthing system and wear antistatic - LC50: Lethal Concentration 50% The following sections were modified: P103 NDS Absorbs and disolves in water and in organic solvents. With air it may slowly form explosive peroxides. POL Read label before use. 200 400 the provisions of (EU) Regulation 2015/830. flames to prevent explosions. Rapidly degradable On the basis of available data, the product does not contain any PBT or vPvB in percentage greater than 0,1%. the provisions of (EU) Regulation 2015/830. Incompatible with: oxidising substances,strong acids,alkaline metals. LD50 (Oral) Skin Irrit. 2 H315, STOT SE 3 H335, STOT SE 3 H336 790 mg/kg Rat footwear. Vigorous stirring and flow through the tubes and equipment may cause the formation and accumulation - LD50: Lethal dose 50% P501 OEL narcosis, often preceded by dizziness and associated with headache (Ispesl). Is irritating for skin, EU Dispose of contents / container to . . . 442 100 ETHYL ACETATE 884 200 SKIN 15.2. Chemical safety assessment Any additional information concerning the risks for health and/or the environment are given in sections 11 and 12 EC 02 / 11. LD50 (Dermal) Toxic for aspiration Any additional information concerning the risks for health and/or the environment are given in sections 11 and 12 conjunctiva and respiratory tract. 200-751-6 BARIUM SULFATE 3400 mg/kg Rabbit of electrostatic charges. In order to avoid the risk of fires and explosions, never use compressed air when of this sheet. Threshold Limit Value ETHYL ACETATE TRIZINC BIS (ORTHOPHOSPHATE) - OEL: Occupational Exposure Level of this sheet. TLV-ACGIH LC50 (Inhalation) 87 20 8000 ppm/4h Rat 5.2. Special hazards arising from the substance or mixture

Other hazards

INDEX Threshold Limit Value IATA: 603-004-00-6 NO 9.1. Information on basic physical and chemical properties handling. Open containers with caution as they may be pressurised. Do not eat, drink or smoke during use. Avoid Solubility in water

PBT Substances

Persistent bioaccumulative and toxic as REACH Regulation Type Decomposes slowly into acetic acid and ethanol under the effect of light, air and water. Country TWA/8h 2,7 mg/l STEL/15min

ECOLOGICAL INFORMATION

ZINC OXIDE No chemical safety assessment has been processed for the mixture and the substances it contains. leakage of the product into the environment. Incompatible with: acids,bases,strong oxidants,aluminium,nitrates,chlorosulphuric acid.Incompatible materials:

Contains

Type N-METHYL-2-PYRROLIDONE Country TWA/8h N-METHYL-2-PYRROLIDONE STEL/15min Hazard classification and indication: Degradability: information not available Information not available - PEC: Predicted environmental Concentration Hazard classification and indication: CAS HAZARDS CAUSED BY EXPOSURE IN THE EVENT OF FIRE plastic materials. 1-METHOXY-2-PROPANOL There are no reported cases of acute or chronic intoxication or sensitisation. On volunteers, repeated skin 1314-13-2 1 ≤ x < 1,5 mg/m3 ppm Aquatic Acute 1 H400 M=1, Aquatic Chronic 1 H410 M=1 mg/m3 ppm 10.2. Chemical stability For Air transport, environmentally hazardous mark is only mandatory for UN 3077 and UN 3082. Properties TLV LD50 (Oral) BGR mg/m3 800 ppm Value mg/m3 ppm 5300 mg/kg Rat BUTANOL H226 Flammable liquid and vapour. Information

Further information

PEL: Predicted exposure level EC Excess pressure may form in containers exposed to fire at a risk of explosion. Do not breathe combustion This product is dangerous for the environment and is toxic for aquatic organisms. In the long term, it have negative Flammable liquid, category 3 applications caused modest and transient erythema. Oral and inhalation trials on mice and rats revealed no 215-222-5 7.2. Conditions for safe storage, including any incompatibilities 10.6. Hazardous decomposition products Threshold Limit Value Appearance ZINC OXIDE TLV Aspiration hazard, category 1 TLV Aspiration hazard, category 1 LD50 (Dermal) BGR CZE 700 10 liquid 13000 mg/kg Rabbit 900 H304 May be fatal if swallowed and enters airways. SECTION 13. Disposal considerations 14.6. Special precautions for user effects on acquatic environment. - PNEC: Predicted no effect concentration INDEX products. VOC (Directive 2004/42/EC) : teratogenic effects at non embryotoxic doses. Not mutagenic in the Ames test. 030-013-00-7 Colour The product is stable in normal conditions of use and storage. Solubility in water WEL Type VLEP LC50 (Inhalation) GBR Country TWA/8h FRA 1400 4 400 light grey 2,9 mg/l STEL/15min 54,6 mg/l/4h Rat H373 May cause damage to organs through prolonged or repeated Text of hazard (H) indications mentioned in section 2-3 of the sheet: - REACH: EC Regulation 1907/2006 Two-pack performance coatings. N-METHYL-2-PYRROLIDONE Specific target organ toxicity - repeated Store only in the original container. Store the containers sealed, in a well ventilated place, away from direct Solubility in water OEL EU 0,5 0,1 - 100 mg/l 5.3. Advice for firefighters mg/m3 12.1. Toxicity 13.1. Waste treatment methods Odour In the event of thermal decomposition or fire, gases and vapours that are potentially dangerous to health may be - RID: Regulation concerning the international transport of dangerous goods by train VOC given in g/litre of product in a ready-to-use condition : CAS sunlight. Store in a well ventilated place, keep far away from sources of heat, naked flames and sparks and other ADR / RID: exposure, category 2 WEL exposure, category 2 1-METHOXY-2-PROPANOL 872-50-4 exposure. GBR HIN - Kemler: 33 0,35 ≤ x < 0,4 Repr. 1B H360D, Eye Irrit. 2 H319, Skin Irrit. 2 H315, STOT SE 3 H335 ppm 200 Not available mg/m3 ppm Limited Quantities: 5 L 400 455,50 Tunnel restriction code: (D/E) N-METHYL-2-PYRROLIDONE Degradability: information not available Odour threshold released. TLV-ACGIH Eye irritation, category 2 TLV Eye irritation, category 2 TRIZINC BIS (ORTHOPHOSPHATE) CZE GRC - TLV: Threshold Limit Value Limit value: EC sources of ignition. Keep containers away from any incompatible materials, see section 10 for details. Flam. Liq. 2 The main route of entry is the skin, whereas the respiratory route is less important due to the low vapour 1400 300 5 212-828-1 400

Special Provisions

640D Not available Flammable liquid, category 2 600 H319 Causes serious eye irritation. SKIN 500,00 GENERAL INFORMATION pH NOT rapidly degradable Reuse, when possible. Product residues should be considered special hazardous waste. The hazard level of Is stable up to 315°C/599°F. Skin irritation, category 2 VLEP NDS Skin irritation, category 2 LD50 (Oral) FRA POL - TLV CEILING: Concentration that should not be exceeded during any time of occupational exposure. - Thinned with : INDEX IMDG: Flam. Liq. 3 pressure of the product. Above 100 ppm causes irritation of the eye, nose and oropharynx mucous 734 606-021-00-7 EMS: F-E, S-E Not available Flammable liquid, category 3 1468 > 5000 mg/kg Rat - Wistar 150 H315 50 10,00 % Limited Quantities: 5 L Causes skin irritation. THINNER 125 Use jets of water to cool the containers to prevent product decomposition and the development of substances Melting point / freezing point ETHYLBENZENE TRIZINC BIS (ORTHOPHOSPHATE) waste containing this product should be evaluated according to applicable regulations. Specific target organ toxicity - single WEL OEL Specific target organ toxicity - single LC50 (Inhalation) membranes. At 1000 ppm, disturbance of equilibrium and severe eye irritation can be noticed. Clinical and GBR EU 734 200 Not available > 5,7 mg/l Rat 1468 154 H335 400 50 May cause respiratory irritation. SKIN May cause respiratory irritation. 7.3. Specific end use(s) 10.3. Possibility of hazardous reactions - TWA STEL: Short-term exposure limit 1-METHOXY-2-PROPANOL IATA: Repr. 1B Cargo: Reproductive toxicity, category 1B Maximum quantity: 60 L Packaging instructions: 364 12.3. Bioaccumulative potential Initial boiling point potentially hazardous for health. Always wear full fire prevention gear. Collect extinguishing water to prevent it LC50 - for Fish Disposal must be performed through an authorised waste management firm, in compliance with national and local May develop: methane,styrene,hydrogen,ethane. exposure, category 3 TLV TLV-ACGIH exposure, category 3 biological examinations carried out on exposed volunteers revealed no anomalies. Acetate produces greater GRC 1441 300 100 400 > 35 0,78 mg/l/96h Pimephales promelas °C 300 100 CAS - TWA: Time-weighted average exposure limit SKIN CORROSION / IRRITATION Acute Tox. 4 107-98-2 Pass.: 0,1 ≤ x < 0,15 Flam. Liq. 3 H226, STOT SE 3 H336 Acute toxicity, category 4 Maximum quantity: 5 L Packaging instructions: 353 from draining into the sewer system. Dispose of contaminated water used for extinction and the remains of the fire Boiling range EC50 - for Crustacea regulations. Hazardous to the aquatic environment, NDS Hazardous to the aquatic environment, skin and eye irritation with direct contact. No chronic effects on humans have been reported. POL

2.3 Other hazards

VOC: Volatile organic Compounds EC Information not available The vapours may also form explosive mixtures with the air. Asp. Tox. 1 50 203-539-1 Special Instructions: Not available 0,86 mg/l/48h Daphnia magna Aspiration hazard, category 1 150 H411 A3, A72, A192 Toxic to aquatic life with long lasting effects. according to applicable regulations. Flash point N-METHYL-2-PYRROLIDONE Legend: Waste transportation may be subject to ADR restrictions.

vPvB Substances

Very Persistent and very Bioaccumulative as for REACH Regulation chronic toxicity, category 2 TLV-ACGIH STOT RE 2 chronic toxicity, category 2 Specific target organ toxicity - repeated exposure, category 2 61 < 23 20 °C INDEX Causes skin irritation XYLENE (MIXTURE OF ISOMERS) ZINC OXIDE CONTAMINATED PACKAGING May develop: nitric oxide,carbon oxides. 603-064-00-3 SPECIAL PROTECTIVE EQUIPMENT FOR FIRE-FIGHTERS (C) = CEILING ; INHAL = Inhalable Fraction ; RESP = Respirable Fraction ; THORA = Thoracic Fraction. Evaporation rate Interactive effects On the basis of available data, the product does not contain any PBT or vPvB in percentage greater than 0,1%. - WGK: Water hazard classes (German). Eye Dam. 1 Serious eye damage, category 1 Not available 14.7. Transport in bulk according to Annex II of Marpol and the IBC Code XYLENE (MIXTURE OF ISOMERS) Partition coefficient: n-octanol/water LC50 - for Fish Contaminated packaging must be recovered or disposed of in compliance with national waste management 3,12 1,1 mg/l/96h Oncorhynchus mykiss Normal fire fighting clothing i.e. fire kit (BS EN 469), gloves (BS EN 659) and boots (HO specification A29 and Flammability (solid, gas) Eye Irrit. 2 Eye irritation, category 2 Not available