heterocyclic, amides

SECTION 2: Hazards identification

EXPOSURE LIMITS Emergency overview WARNING: COMBUSTIBLE LIQUID. Irritating to eyes and skin. INGESTION MAY CAUSE GASTRIC DISTURBANCES. A component of this product has been shown to be developmentally toxic in animal studies. Use with local exhaust ventilation. Avoid contact with the skin, eyes and clothing. Wear a NIOSH-certified (or equivalent) organic vapor respirator. Wear chemical resistant protective gloves. Wear NIOSH-certified chemical goggles. Wear protective clothing. Eye wash fountains and safety showers must be easily accessible. State of matter: liquid Color: clear, colorless Odor: mild,amine-like

Principle Routes of Exposure

Routes of entry for solids and liquids include eye and skin contact, ingestion and inhalation. Routes of entry for gases include inhalation and eye contact. Skin contact may be a route of entry for liquified gases. Acute toxicity: Of low toxicity after s ingle injestion. Virtually nontoxic by inhalation. Virtually nontoxic after a single skin contact. Irritation / corrosion: Eye contact causes irritation. Skin contact causes irritation. Causes temporary irritation of the respiratory tract. EU- classification. Assessment other acute effects: Causes temporary irritation of the respiratory tract. Sensitization: Skin sensitizing effects were not observed in animal studies. Chronic toxicity: Carcinogenicity: In long term studies in which the substance was given by inhalation, a carcinogenic effect was not observed. In long term studies in rats in which the substance was given by feed, a carcinogenic effect was not observed. In long term studies in rodents exposed to high doses, a tumorigenic effect was found; however, these results are thought to be due to a rodent specific liver effect that is not relevant to humans. The whole of the information available provides no indication of a carcinogenic effect. Repeated dose toxicity: After repeated exposure the prominent effect is local irritation. The substance may cause damage to the testes after repeated inhalation of high doses. Reproductive toxicity: As shown in animal studies, the product may cause damage to the testes after repeated high exposures that cause other toxic effects.

Teratogenic Effects

The substance caused malformations/developmental toxicity in laboratory animal Genotoxicity: The substance was not mutagenic in bacteria. No mutagenic effect was found in various tests with mammalian cell culture and mammals. Medical conditions aggravated by overexposure: Data available do not indicate that there are medical conditions that are generally recognized as being aggravated by exposure to this substance/product. See MSDS section 11 – Toxicological information.

Environmental effects

Terrestrial toxicity: Study scientifically not justified.