2, 4-D Amine Salt 58% SL

Health hazards

IDENTIFICATION EFFECTS OF OVEREXPOSURE ACUTE (SHORT TERM EXPOSURE): EYE : May cause severe irritation with corneal injury and may result in permanent impairment of vision, even blindness. SKIN CONTACT : Prolonged exposure may cause skin irritation. SKIN ABSORPTI ABSORPTION : A single prolonged skin exposure may result in the materials being absorbed in harmful amounts. INGEASTION : MAY cause gastrointestinal irritation INHALATION : Single exposure to vapors is not likely to be hazardous.

Principle Routes of Exposure

Skin and eye contact, skin absorption, acute inhalation and ingestion Noxious vapors under high temperature conditions. EFFECTS OF OVEREXPOSURE : May cause loss of appetite, nausea, Vomiting, general tenseness and muscular weakness, and prolonged or repeated exposure may lead to liver or kidney damage or central nervous system symptoms. EXPOSURE LIMITS : For 2, 4-D acid TLV -TWA 10 mg/m3. For dimethyl amine 18 mg/m3. IRRITANCY OF PRODUCT: Eyes : marked irritation and corneal injury may occur. SENSITIZATION OF MATERIAL : Pre-existing skin or respiratory disorders may be aggravated by excessive exposure to this material. CHRONIC (LONG TERM EXPOSURE) : Excessive exposure may cause liver, kidney, gastrointestinal and muscular effects. Signs and symptoms of excessive exposure may be nausea and/or vomiting and abdominal cramps and/or diarrhea. Various animal cancer tests have shown no reliable positive association between 2,4-Dexposure and cancer. Epidemiology studies have been both positive and negative with the majority being negative. Birth defects are unlikely. Exposures having no effect on the mother should have no effect on the fetus. Did not cause birth defects in animals; other effects were seen in the fetus only at doses which caused toxic effects to the mother. High dietary levels of 2, 4-D caused toxic effects (weight and viability reduction) in rats on a reproduction test. Has been shown to be negative in some vitro ("test tube") mutagenicity tests and positive in others. Results of mutagenicity tests in animals have been inconclusive. GENERAL

Precautionary statements

Always practice good industrial hygiene; handle with care; avoid personal contact. Do not get into eyes or on skin; do not breathe mist or vapor of product. Do not swallow. Wash hands with soap and water and rinse after handling product. Shower after each shift. Wash all work clothing and completely clean all PPE (personal protective equipment) after each shift.