Note: Ingredients listed on restricted chemical lists
EC/CAS
101-68-8
Name of the chemical
4,4’-Methylenediphenyl diisocyanate
Concentration
10-30%
EC/CAS
9016-87-9
Name of the chemical
4,4'-Methylendiphenyldiisocyanat tech. (Polymeres) MDI, pMDI (in Form atembarer Aerosole, A-Fraktion)
Concentration
10-30%
EC/CAS
5873-54-1
Name of the chemical
2,4’-Methylenediphenyl diisocyanate
Concentration
3-7%
EC/CAS
2536-05-2
Name of the chemical
2,2’-Methylenediphenyl diisocyanate
Concentration
0.1-1%
General Information
Revision date
2025-12-18
Product name
DESMODUR E 21
Chemical name
Aromatic Isocyanate
1.2.1 Relevant identified uses
Raw material for coatings, inks, adhesives, sealants, or elastomers in industrial applications
Icons in SDS
Company Information
company name
Covestro LLC
GHS Information
Signal word
Danger
Hazard Codes
Hazard statements (CLP)
H315, H317, H332, H334, H335, H372
Hazard statements
Code
Statements
H315
Causes skin irritation
Section 2
SECTION 2: Hazards identification
GHS Classification Acute toxicity (Inhalation) Category 4 Skin irritation Category 2 Eye irritation Category 2B Respiratory sensitisation Category 1 Skin sensitisation Category 1 Specific target organ toxicity - Category 3 (Respiratory system) single exposure Specific target organ toxicity - Category 1 (Respiratory tract) repeated exposure
Signal word
Danger
Hazard statements
Causes skin and eye irritation. May cause an allergic skin reaction. Harmful if inhaled. May cause allergy or asthma symptoms or breathing difficulties if inhaled. May cause respiratory irritation. Causes damage to organs (Respiratory tract) through prolonged or repeated exposure if inhaled.
Prevention
Wear protective gloves. Wash skin and face thoroughly after handling. Contaminated work clothing must not be allowed out of the workplace. Do not breathe dust, mist, gas, vapors or spray. In case of inadequate ventilation wear respiratory protection. The type of respiratory protection selected must comply with the requirements set forth in OSHA's Respiratory Protection Standard (29 CFR 1910.134) or regional standards. For additional details, see section 8 of the SDS. Do not eat, drink or smoke when using this product. Use only outdoors or in a well-ventilated area.
Response
IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove person to fresh air and keep comfortable for breathing. Get medical advice/ attention if you feel unwell. If skin irritation or rash occurs: Get medical attention. If eye irritation persists: Get medical attention. If experiencing respiratory symptoms: Call a doctor or emergency medical facility (i.e. 911). IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Take off contaminated clothing and wash it before reuse.
Storage
Store in a well-ventilated place. Keep container tightly closed. Store locked up.
Disposal
Dispose of contents and container in accordance with existing federal, state, and local environmental control laws.
2.1 Classification of the substance or mixture
Acute toxicity (Inhalation): Category 4 Skin irritation: Category 2 Eye irritation: Category 2B Respiratory sensitisation: Category 1 Skin sensitisation: Category 1 Specific target organ toxicity - Category 3 (Respiratory system) single exposure: Specific target organ toxicity - Category 1 (Respiratory tract) repeated exposure