Note: Ingredients listed on restricted chemical lists
EC/CAS
227-534-9/5873-54-1
Name of the chemical
2,4’-Methylenediphenyl diisocyanate
Concentration
>=5% >=5% >=0,1% >=5%
EC/CAS
202-966-0/101-68-8
Name of the chemical
4,4’-Methylenediphenyl diisocyanate
Concentration
>=5% >=5% >=0,1% >=5%
EC/CAS
219-799-4/2536-05-2
Name of the chemical
2,2’-Methylenediphenyl diisocyanate
Concentration
>=5% >=5% >=0,1% >=5%
General Information
Version
17.0
Revision date
2026-07-07
Product name
DESMODUR 2460 M
1.2.1 Relevant identified uses
Hardener for coating materials or adhesives For details of the identified uses according to REACH-Regulation (EU) No. 1907/2006 refer to the annex of this safety data sheet
1.2.2. Uses advised against
Consumer spray application is not supported Consumer applications that require heating above room temperature before or during use are not supported Professional cleaning activities with Aprotic Polar Solvents are not supported
Emergency telephone
+1-703-527-3887
Icons in SDS
Company Information
company name
Covestro Deutschland AG
e-mail address of the competent person responsible for the Safety Data Sheet
SafetyDataSheet-Support-EMLA@cx.covestro.com
GHS Information
Signal word
Danger
Hazard Codes
Hazard statements (CLP)
H315, H317, H319, H332, H334, H335, H351, H373
Hazard statements
Code
Statements
H315
Causes skin irritation
Section 2
SECTION 2: Hazards identification
Classification of the substance or mixture Acute toxicity, Inhalative, Category 4 (H332) Skin irritation, Category 2 (H315) Eye irritation, Category 2 (H319) Sensitization of the respiratory airways, Category 1 (H334) Sensitization of the skin, Category 1 (H317) Carcinogenicity, Category 2 (H351) Specific target organ toxicity (single exposure), Category 3 (H335 (Respiratory system)) Specific target organ toxicity (repeated exposure), Category 2 (H373)
2.2 Label elements
Danger
Hazardous Ingredients
diphenylmethane-2,4'-diisocyanate 4,4'-methylenediphenyl diisocyanate 2,2'-methylenediphenyl diisocyanate
Hazard statements
H315 Causes skin irritation. H317 May cause an allergic skin reaction. H319 Causes serious eye irritation. H332 Harmful if inhaled. H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled. H335 May cause respiratory irritation. H351 Suspected of causing cancer. H373 May cause damage to organs through prolonged or repeated exposure.
Precautionary statements
P201 Obtain special instructions before use. P260 Do not breathe mist or vapours. P264 Wash skin thoroughly after handling. P280 Wear protective gloves/ protective clothing/ eye protection/ face protection/ hearing protection. P304 + P340 + P312 IF INHALED: Remove person to fresh air and keep comfortable for breathing. Call a POISON CENTER/ doctor if you feel unwell. P342 + P311 If experiencing respiratory symptoms: Call a POISON CENTER or doctor/ physician. Supplementary hazardous characteristics and labeling elements: EUH204 Contains isocyanates. May produce an allergic reaction. "As from 24 August 2023 adequate training is required before industrial or professional use."
2.3 Other hazards
In case of hypersensitivity of the respiratory tract (e.g. asthmatics and those who suffer from chronic bronchitis) it is inadvisable to work with the product. Symptoms affecting the respiratory tract can also occur several hours after overexposure. Dust, vapors and aerosols are the primary risk to the respiratory tract. This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
2.1 Classification of the substance or mixture
Acute toxicity, Inhalative, Category 4 (H332) Skin irritation, Category 2 (H315) Eye irritation, Category 2 (H319) Sensitization of the respiratory airways, Category 1 (H334) Sensitization of the skin, Category 1 (H317) Carcinogenicity, Category 2 (H351) Specific target organ toxicity (single exposure), Category 3 (H335 (Respiratory system)) Specific target organ toxicity (repeated exposure), Category 2 (H373)
