A-304

SECTION 2: Hazards identification

EFFECTS OF SINGLE OVEREXPOSURE: SWALLOWING: Slightly toxic. May cause nausea, abdominal discomfort, vomiting, and diarrhea. Swallowing large quantities may lead to central nervous system disturbances, such as convulsions, depression, or coma. Aspiration into the lungs may occur during ingestion or vomiting, resulting in lung injury. SKIN ABSORPTION: No evidence of adverse effects from available information. INHALATION: Causes irritation of the respiratory tract, experienced as nasal discomfort and discharge with chest pain and coughing. Dizziness and drowsiness may occur. Eye irritation may occur. Severed overexposure by inhalation may result in permanent lung damage. SKIN CONTACT: Brief contact not irritating. Prolonged contact, as from wet clothing from material, may cause moderate irritation with redness and slight burn. EYE CONTACT: Liquid and Vapor may cause irritation, experienced as stinging with excess blinking and tear production. Redness and swelling of the conjunctiva may occur. High vapor concentration may cause same symptoms. EFFECTS OF REPEATED OVEREXPOSURE: Inhalation over a prolonged period will produce symptoms of dizziness, weakness, pain in the limbs, paresthesias, nervousness, and lead to anemia and weight loss. Repeated overexposure to Tetra (2-meethoxyethoxy) silane may cause injury to bone marrow, blood cells, and testes.

Medical Conditions Generally Aggravated by Exposure

OVEREXPOSURE Because of its irritating and defatting properties, this material may aggravate and existing dermatitis. SIGNIFICANT LABORATORY DATA WITH POSSIBLE RELEVANCE TO HUMAN HEALTH HAZAPD EVA LUATION: Prolonged and repeated inhalation exposure to hydrocarbon vapor in the same boiling range has produced kidney damage in male rats. This effect has not been observed in female rats and male and female mice. The relevance of this information to humans is unknown. The EPA has expressed concern regarding the possible adverse health effects resulting from the inhalation of alkoxysilanes and has recommended that administrative and mechanical means be used to minimize exposure. n-Propanol (which is generated upon exposure to water and or mosture has been demonstrated to be carcinogenic in lifetime expsure studies in rats when administered orally or subcutaneously. OTHER EFFECTS OF OVEREXPOSURE None currently known.