PANACUR Suspension 5-10%

EU Classification

Repr.Cat.3;R63 N;R50/53 EMERGENCY OVERVIEW White Suspension Odorless May be irritating to eyes, skin or respiratory tract. May be harmful if swallowed. May cause effects to: liver kidney gastrointestinal tract stomach immune system blood central nervous system fetus Very toxic to aquatic organisms. May cause long-term adverse effects in the aquatic environment.

Potential health effects

The information presented below pertains to the following individual ingredients, and not to the mixture(s). Only information about the ingredients that are expected to contribute significantly to the potential health hazard profile of the formulation(s) are presented. The active ingredient fenbendazole is a benzimidazole carbamate anthelmintic that is structurally related to mebendazole. Therapeutic use of mebendazole, a substance of the same chemical class as fenbendazole, has been reported to cause gastrointestinal disturbances (transient abdominal pain), diarrhea, headache, and dizziness. Frequent effects reported after treatment with high-doses of mebendazole have included allergic reactions (fever and skin reactions), raised liver enzyme values, alopecia, bone marrow depression, reduced leucocyte count and raised serum-transaminase values. A number of oral subchronic and chronic animal studies have been conducted with fenbendazole and have demonstrated that the liver is the main target tissue. In addition, stomach, kidneys, blood, immune system, and central nervous system are also affected by treatment with fenbendazole. Devlopmental effects have been reported in rabbits following treatment with fenbendazole. LISTED CARCINOGENS No carcinogens or potential carcinogens listed by IARC or EU Directive 90/394 (Annex I) in this mixture.