ElastoFil 75

Principle Routes of Exposure

Skin Contact from liquid and aerosols (spray application) Inhalation. Although MDI is low in volatility, an inhalation hazard can exist from MDI aerosols or vapors formed during heating, foaming or spraying. HUMAN EFFECTS AND SYMPTOMS OF OVER-EXPOSURE: ACUTE INHALATION: MDI vapors or mist at concentrations above the TLV can irritate (burning sensation) the mucous membranes in the respiratory tract (nose, throat, lungs) causing runny nose, sore throat, coughing, chest discomfort, shortness of breath and reduced lung function (breathing obstruction). Persons with a pre-existing, nonspecific bronchial hyper-reactivity can respond to concentrations below the TLV with similar symptoms as well as asthma attack. Exposure well above the TLV may lead to bronchitis, bronchial spasm and pulmonary edema (fluid in lungs). These effects are usually reversible. Chemical or hypersensitive pneumonitis, with flu-like symptoms (e.g., fever, chills) has also been reported. These symptoms can be delayed up to several hours after exposure. CHRONIC INHALATION: As a result of previous repeated overexposures or a single large dose, certain individuals develop isocyanate sensitization (chemical asthma) which will cause them to react to a later exposure to isocyanate at levels well below the TLV. These symptoms, which can include chest tightness, wheezing, cough, shortness of breath or asthma attack, could be immediate or delayed (up to several hours after exposure). Similar to many non-specific asthmatic responses, there are reports that once sensitized an individual can experience these symptoms upon exposure to dust, cold air or other irritants. This increased lung sensitivity can persist for weeks and in severe cases for several years. Overexposure to isocyanates has also been reported to cause lung damage (including decrease in lung function) which may be permanent. Sensitization can either be temporary or permanent. ACUTE SKIN CONTACT: Isocyanates react with skin protein and moisture and can cause irritation which may include the following symptoms: reddening, swelling, rash, scaling or blistering. Cured material is difficult to remove. CHRONIC SKIN CONTACT: Prolonged contact can cause reddening, swelling, rash, scaling, blistering, and in some cases, skin sensitization. Individuals who have skin sensitization can develop these symptoms from contact with liquid or vapors. Animal tests have indicated that respiratory sensitization can result from skin contact with MDI. This data reinforces the need to prevent direct skin contact with MDI. (See Toxicological Information, SENSITIZATION.) ACUTE EYE CONTACT: Liquid, aerosols or vapors are irritating and can cause tearing, reddening and swelling. If left untreated, corneal damage can occur and injury is slow to heal. However, damage is usually reversible. See First Aid Measures for treatment. CHRONIC EYE CONTACT: None found. ACUTE INGESTION: Can result in irritation and corrosive action in the mouth, stomach tissue and digestive tract. Symptoms can include sore throat, abdominal pain, nausea, vomiting and diarrhea. CHRONIC INGESTION: None found. CARCINOGENICITY: Neither MDI nor polymeric MDI are listed by the NTP, IARC or regulated by OSHA as carcinogens. NTP—– - - - - - Not listed IARC— - - - - - Not listed OSHA— - - - - Not regulated OTHER— - - - See results of two year inhalation study in Toxicological Information, CARCINOGENICITY. MEDICAL CONDITIONS: Aggravated by Exposure: Asthma, other respiratory disorders (bronchitis, emphysema, bronchial hyper-reactivity), skin allergies, eczema.