COAGULATION PATHOLOGIC CONTROL

SECTION 2: Hazards identification

OSHA - This product must be classified, according to directive 2001/58/EC, as non hazardous. - May cause irritation. May cause central nervous system effects. - Each unit of source material used in the preparation of this product has been tested by an FDA licensed method and found non-reactive for HBsAg and negative for antibodies to HIV and HCV. However, no known test method can offer complete assurance that products derived from human blood will not transmit hepatitis, AIDS, or other infectious diseases. This product, like all materials of human origin, should be handled as potentially infectious biological material. 4. FIRST AID MEASURES - Eye contact: Immediately flush eyes with plenty of water for at least 15 minutes, lifting the upper and lower eyelids. Seek immediate medical advice. - Skin contact: Wash skin with plenty of soap and water. Get medical aid. - Ingestion: If victim is conscious and alert, drink immediately large amounts of water or 2- 4 cupfuls of milk. Get medical aid. SDS128-I CHEMELEX SAFETY DATA SHEET FOR REAGENT Ed/Rev 1/0 2/3 - Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. - Notes to Physician: Treat symptomatically and supportively. 5. FIRE-FIGHTING MEASURES - Extinguishing media: As appropriate to the environment. For small fires use water spray, dry chemical powder, carbon dioxide or chemical foam. - Thermal decomposition: Not known. 6. ACCIDENTAL RELEASE MEASURES - Individual precautions: Use proper personal protective equipment as indicated in - Methods for collection / Sweep up and collect up with absorbent inert materials cleaning: (vermiculite, sand or earth, etc) and deposit into a suitable disposal container in accordance with current legislation. Clean any remains with plenty of water. 7. HANDLING AND STORAGE - Handling: Avoid contact with the skin and eyes. Avoid ingestion and inhalation. Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation.

Storage

Store in a cool, dry, well ventilated place, and protect from sunlight. Keep in the original container, well sealed. 8. EXPOSURE CONTROLS / PERSONAL PROTECTION - Engineering controls: Good general ventilation should be sufficient to control airborne levels. - Exposure Limits: EC CAS CHEMICAL NUMBERS ACGIH NIOSH OSHA NAME EINECS / ELINCS 1310-73-2 Sodium 215-185-5 2 mg/m3 10 mg/m3 IDLH 2 mg/m3 TWA hydroxide Ceiling 2 mg/m3 Ceiling 7727-43-7 Barium 231-784-4 10 mg/m3 TWA 10 mg/m3 TWA (total dust) 15 mg/m3 TWA (total dust) sulphate 5 mg/m3 TWA (resp. dust) 5 mg/m3 TWA (resp. fract.) - Respiratory protection: Always use a European Standard EN 149 approved respiration when necessary. - Hand protection: Wear appropriate protective gloves to prevent skin exposure. - Eye protection: Wear appropriate protective eyeglasses or chemical safety goggles as described by European Standard EN 166. - Hygiene measures: Wash hands before breaks and after work. Do not eat, drink or smoke in the workplace. 9. STABILITY AND REACTIVITY - Chemical Stability: Stable under normal temperatures and pressures. SDS128-I CHEMELEX SAFETY DATA SHEET FOR REAGENT Ed/Rev 1/0 3/3 - Incompatibilities with other Materials: None reported. - Hazardous Decomposition Products: None. 10. TOXICOLOGICAL INFORMATION Quantitative data on the toxicity of this product are not available. THE FOLLOWING APPLIES TO THE MAIN COMPOUNDS: Acute tocicity: CAS LD50/LC50: 1310-73-2 Draize test, rabbit, eye: 1 % Severe Draize test, rabbit, skin: 500 mg/24H Severe 7447-41-8 Draize test, rabbit, eye: 100 mg/24H Moderate Oral, rabbit: LD50 = 775 mg/kg Draize test, rabbit, skin: 500 mg/24H Severe. Skin, rabbit: LD50 = 1629 mg/kg Oral, mouse: LD50 = 1165 mg/kg Skin, rat: LD50 = 1488 mg/kg Potential dangerous health effects: - If inhaled : Prolonged exposure may result in dizziness and general weakness. - Upon contact with the skin: Prolonged and/or repeated contact may cause irritation and/or dermatitis. - Through contact with eyes: May cause eye irritation. - If swallowed: May cause gastrointestinal irritation. 11. ECOLOGICAL INFORMATION Ecological data for this product is not available. No ecological problems are expected when the product is handled and used with due care and attention.