4-METHYLPENTAN-2-ONE

Hazard statements (CLP)

H225, H319, H332, H335, H351

Code

Statements

H225

Highly Flammable liquid and vapour

2.1 Classification of the substance or mixture

Eye Damage/Irritation: Category 2A of the Flammable Liquids: Category 2 substance/mixture Acute Toxicity - Inhalation: Category 4 Specific target organ toxicity - Single Exposure Category 3, Respiratory system Carcinogenicity: Category 2

Signal word

DANGER

Hazard statements

H225 Highly flammable liquid and vapour. (s) H319 Causes serious eye irritation. H332 Harmful if inhaled. H335 May cause respiratory irritation. H351 Suspected of causing cancer. AUH066 Repeated exposure may cause skin dryness and cracking.

Hazard pictograms

Flame, Health hazard, Exclamation mark

Prevention

P210 Keep away from heat/sparks/open flames/hot surfaces. – No smoking. P201 Obtain special instructions before use. P202 Do not handle until all safety precautions have been read and understood. P233 Keep container tightly closed. P240 Ground/bond container and receiving equipment. P241 Use explosion-proof electrical/ventilating/lighting/.../equipment. P242 Use only non-sparking tools. P243 Take precautionary measures against static discharge. P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P264 Wash thoroughly after handling. P271 Use only outdoors or in a well-ventilated area. P280 Wear protective gloves/protective clothing/eye protection/face protection. P281 Use personal protective equipment as required.

Response

P303+P361+P353 IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P337+P313 If eye irritation persists: Get medical advice/attention. P304+P340 IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P312 Call a POISON CENTER or doctor/physician if you feel unwell. P308+P313 IF exposed or concerned: Get medical advice/attention. P370+P378 In case of fire: Use foam, dry chemical, CO2 or water spray for extinction. Precautionary P403+P233+P325 Store in a well-ventilated place. Keep container tightly closed. Keep cool.

Storage

Precautionary P501 Dispose of contents/container to relevant local, state and federal government regulations.

Further information

Toxicologically Synergistic Materials: In studies with mice, MIBK prolonged the loss of righting reflex induced by ethanol. In animal studies, MIBK has been shown to potentiate the hepatotoxicity of haloalkanes, such as chloroform, carbon tetrachloride and 1,2-dichlorobenzene. Combined exposure to methyl ethyl ketone and MIBK caused increased behavioural responses in baboons. Potential for Accumulation: MIBK does not accumulate in the body.