PTMScan Phospho-Enrichment IMAC Fe-NTA Magnetic Beads

Hazard statements (CLP)

H226

Code

Statements

H226

Flammable liquid and vapour

SECTION 2: Hazards identification

OSHA Classification

Signal word

Warning

Hazard statements

Flammable liquid and vapor. .

Precautionary statements

Wear protective gloves/protective clothing/eye protection/face protection. Keep away from heat/sparks/open flames/hot surfaces. _____________________________________________________________________________________________ Page 1 / 7 20432 - PTMScan® Phospho-Enrichment IMAC Fe-NTA Magnetic Revision Date: 2016-08-05 Beads _____________________________________________________________________________________________ Sensitivity to Static Discharge Yes. Protective Equipment and Precautions for Firefighters As in any fire, wear self-contained breathing apparatus pressure-demand, MSHA/NIOSH (approved or equivalent) and full protective gear. SECTION 6. Accidental release measures Personal precautions, protective equipment and emergency procedures For non-emergency personnel Evacuate personnel to safe areas. Ensure adequate ventilation. Remove all sources of ignition. Take precautionary measures against static discharges. All equipment used when handling the product must be grounded. Do not touch damaged containers or spilled material unless wearing appropriate protective clothing. Use personal protective equipment.

Further information

No information available. Environmental precautions Beware of vapors accumulating to form explosive concentrations. Vapors can accumulate in low areas. Methods and material for containment and cleaning up Methods for containment Prevent further leakage or spillage if safe to do so. Methods for cleaning up Soak up with inert absorbent material (e.g. sand, silica gel, acid binder, universal binder, sawdust). Pick up and transfer to properly labeled containers. Clean contaminated surface thoroughly. SECTION 7. Handling and storage Precautions for safe handling Avoid contact with skin, eyes and clothing. Do not breathe vapors or spray mist. Wear personal protective equipment. Remove and wash contaminated clothing before re-use. Keep away from open flames, hot surfaces and sources of ignition. Take precautionary measures against static discharges. Use only in an area containing flame proof equipment. Conditions for safe storage, including any incompatibilities Technical measures/Storage Keep container tightly closed in a dry and well-ventilated place. Keep away from open conditions flames, hot surfaces and sources of ignition. Packaging material No information available. Incompatible products None known based on information supplied. SECTION 8. Exposure controls/personal protection Control parameters Chemical Name ACGIH TLV Softening point No information available Molecular Weight No information available VOC content No information available Density No information available. Bulk Density VALUE No information available. SECTION 10. Stability and reactivity Reactivity No information available. _____________________________________________________________________________________________ Page 4 / 7 20432 - PTMScan® Phospho-Enrichment IMAC Fe-NTA Magnetic Chemical stability Stable under recommended storage conditions. Possibility of hazardous reactions Hazardous reactions None under normal processing. Hazardous polymerization None under normal processing. Conditions to Avoid Heat, flames and sparks. Extremes of temperature and direct sunlight. Incompatible Materials None known based on information supplied. Hazardous Decomposition Products None known based on information supplied. SECTION 11. Toxicological information Information on likely routes of exposure Inhalation There is no data available for this product. Avoid breathing vapors or mists. Vapours may irritate throat and respiratory system. Eye contact There is no data available for this product. Avoid contact with eyes. Contact with eyes may cause irritation. Skin contact There is no data available for this product. Avoid contact with skin. Prolonged or repeated contact may dry skin and cause irritation. Ingestion There is no data available for this product. Ingestion may cause gastrointestinal irritation, nausea, vomiting and diarrhea. May cause central nervous system depression. Information on toxicological effects This material should only be handled by, or under the close supervision of, those properly qualified in the handling and use of potentially hazardous chemicals. It should be borne in mind that the toxocological and physiological properties of this compound is not well defined. Chemical Name LD50 Oral LD50 Dermal LC50 Inhalation ethanol 7060 ( Rat ) - Delayed and immediate effects as well as chronic effects from short and long-term exposure Symptoms Symptoms of overexposure may be headache, dizziness, tiredness, nausea and vomiting. Sensitization No information available. Mutagenic effects No information available. Carcinogenicity Contains no ingredient listed as a carcinogen. Ethanol has been shown to be carcinogenic in long-term studies only when consumed as alcoholic beverage. Contains a suspected carcinogen. However, this component is not at a concentration considered for classification. Based on available data, the classification criteria are not met. Reproductive toxicity No information available. STOT - single exposure No information available. STOT - repeated exposure No information available. Neurological effects No information available. Aspiration Hazard No information available. SECTION 12. Ecological information Ecotoxicity Harmful to aquatic life _____________________________________________________________________________________________ Page 5 / 7 20432 - PTMScan® Phospho-Enrichment IMAC Fe-NTA Magnetic Revision Date: 2016-08-05 Beads _____________________________________________________________________________________________ Reactive Hazard No Clean Water Act This product does not contain any substances regulated as pollutants pursuant to the Clean Water Act (40 CFR 122.21 and 40 CFR 122.42). CERCLA This material, as supplied, does not contain any substances regulated as hazardous substances under the Comprehensive Environmental Response Compensation and Liability Act (CERCLA) (40 CFR 302) or the Superfund Amendments and Reauthorization Act (SARA) (40 CFR 355). There may be specific reporting requirements at the local, regional, or state level pertaining to releases of this material. California Proposition 65 Ethyl alcohol is only a considered a Proposition 65 developmental hazard when it is ingested as an alcoholic beverage. Chemical Name California Prop. 65 ethanol Carcinogen Developmental U.S. State Right-to-Know Regulations Chemical Name New Jersey Massachusetts Pennsylvania ethanol Listed U.S. FIFRA Label Information This product does not contain any substances regulated as pesticides. US Commerce Department - Export Administration Regulations Information This product does not contain any substances regulated under the Chemical Weapons Convention (CWC). U.S. Drug Enforcement Administration Information This product does not contain any substances regulated under the DEA.

Remarks

Method pH 6.5 @ 20 °C Melting point/freezing point Initial boiling point and boiling range Flash point approx. 36 (23 - <=60) °C (based on components) Evaporation rate No information available Flammability (solid, gas) No information available Upper flammability limit 15.0% Lower flammability limit 3.5% Vapor pressure 59 hPa 44 mmHg Vapor density No information available Relative density No information available Solubility dispersible Solubility in other solvents No information available. Partition coefficient: n-octanol/waterNo information available Autoignition temperature 425 °C Decomposition temperature No information available Viscosity No information available Viscosity, dynamic No information available Explosive properties No information available Oxidizing properties No information available

2.1 Classification of the substance or mixture

This substance/mixture is considered hazardous by the 2012 OSHA Hazard Communication Standard (29 CFR 1910.1200) Flammable liquids Category 3 GHS Label elements, including precautionary statements Signal Word Warning Hazard statement(s) Flammable liquid and vapor. . Precautionary Statement(s) Wear protective gloves/protective clothing/eye protection/face protection. Keep away from heat/sparks/open flames/hot surfaces. _____________________________________________________________________________________________ Page 1 / 7 20432 - PTMScan® Phospho-Enrichment IMAC Fe-NTA Magnetic Revision Date: 2016-08-05 Beads _____________________________________________________________________________________________ Sensitivity to Static Discharge Yes. Protective Equipment and Precautions for Firefighters As in any fire, wear self-contained breathing apparatus pressure-demand, MSHA/NIOSH (approved or equivalent) and full protective gear. SECTION 6. Accidental release measures Personal precautions, protective equipment and emergency procedures For non-emergency personnel Evacuate personnel to safe areas. Ensure adequate ventilation. Remove all sources of ignition. Take precautionary measures against static discharges. All equipment used when handling the product must be grounded. Do not touch damaged containers or spilled material unless wearing appropriate protective clothing. Use personal protective equipment. Other information No information available. Environmental precautions Beware of vapors accumulating to form explosive concentrations. Vapors can accumulate in low areas. Methods and material for containment and cleaning up Methods for containment Prevent further leakage or spillage if safe to do so. Methods for cleaning up Soak up with inert absorbent material (e.g. sand, silica gel, acid binder, universal binder, sawdust). Pick up and transfer to properly labeled containers. Clean contaminated surface thoroughly. SECTION 7. Handling and storage Precautions for safe handling Avoid contact with skin, eyes and clothing. Do not breathe vapors or spray mist. Wear personal protective equipment. Remove and wash contaminated clothing before re-use. Keep away from open flames, hot surfaces and sources of ignition. Take precautionary measures against static discharges. Use only in an area containing flame proof equipment. Conditions for safe storage, including any incompatibilities Technical measures/Storage Keep container tightly closed in a dry and well-ventilated place. Keep away from open conditions flames, hot surfaces and sources of ignition. Packaging material No information available. Incompatible products None known based on information supplied. SECTION 8. Exposure controls/personal protection Control parameters Chemical Name ACGIH TLV OSHA PEL NIOSH REL ethanol STEL 1000 ppm TWA : 1000 ppm IDLH : 3300 ppm TWA : 1900 mg/m3 TWA : 1000 ppm TWA : 1900 mg/m3 Appropriate engineering controls Showers, eyewash stations, and ventilation systems. Individual protection measures, such as personal protective equipment _____________________________________________________________________________________________ Page 3 / 7 20432 - PTMScan® Phospho-Enrichment IMAC Fe-NTA Magnetic Revision Date: 2016-08-05 Beads _____________________________________________________________________________________________ Personal protective equipment (PPE) needs to be selected depending on the implemented engineering controls, frequency/duration of work activities and the concentrations of the hazardous substance. Eye/face protection If splashes are likely to occur, wear:. Tightly fitting safety goggles. Skin and body protection Wear protective gloves/clothing. Chemical resistant apron. Lightweight protective clothing. Antistatic boots. Respiratory protection If exposure limits are exceeded or irritation is experienced, NIOSH/MSHA approved respiratory protection should be worn. Positive-pressure supplied air respirators may be required for high airborne contaminant concentrations. Respiratory protection must be provided in accordance with current local regulations. Hygiene measures Handle in accordance with good industrial hygiene and safety practice. Keep away from food, drink and animal feeding stuffs. Do not eat, drink or smoke when using this product. Remove and wash contaminated clothing and gloves, including the inside, before re-use. Provide regular cleaning of equipment, work area and clothing. Wash hands before breaks and immediately after handling the product. SECTION 9. Physical and chemical properties Information on basic physical and chemical properties Physical state Liquid Appearance Suspension Color Clear Odor Characteristic Odor Threshold No information available Property Values Remarks Method pH 6.5 @ 20 °C Melting point/freezing point Initial boiling point and boiling range Flash point approx. 36 (23 - <=60) °C (based on components) Evaporation rate No information available Flammability (solid, gas) No information available Upper flammability limit 15.0% Lower flammability limit 3.5% Vapor pressure 59 hPa 44 mmHg Vapor density No information available Relative density No information available Solubility dispersible Solubility in other solvents No information available. Partition coefficient: n-octanol/waterNo information available Autoignition temperature 425 °C Decomposition temperature No information available Viscosity No information available Viscosity, dynamic No information available Explosive properties No information available Oxidizing properties No information available Other information Softening point No information available Molecular Weight No information available VOC content No information available Density No information available. Bulk Density VALUE No information available. SECTION 10. Stability and reactivity Reactivity No information available. _____________________________________________________________________________________________ Page 4 / 7 20432 - PTMScan® Phospho-Enrichment IMAC Fe-NTA Magnetic Chemical stability Stable under recommended storage conditions. Possibility of hazardous reactions Hazardous reactions None under normal processing. Hazardous polymerization None under normal processing. Conditions to Avoid Heat, flames and sparks. Extremes of temperature and direct sunlight. Incompatible Materials None known based on information supplied. Hazardous Decomposition Products None known based on information supplied. SECTION 11. Toxicological information Information on likely routes of exposure Inhalation There is no data available for this product. Avoid breathing vapors or mists. Vapours may irritate throat and respiratory system. Eye contact There is no data available for this product. Avoid contact with eyes. Contact with eyes may cause irritation. Skin contact There is no data available for this product. Avoid contact with skin. Prolonged or repeated contact may dry skin and cause irritation. Ingestion There is no data available for this product. Ingestion may cause gastrointestinal irritation, nausea, vomiting and diarrhea. May cause central nervous system depression. Information on toxicological effects This material should only be handled by, or under the close supervision of, those properly qualified in the handling and use of potentially hazardous chemicals. It should be borne in mind that the toxocological and physiological properties of this compound is not well defined. Chemical Name LD50 Oral LD50 Dermal LC50 Inhalation ethanol 7060 ( Rat ) - Delayed and immediate effects as well as chronic effects from short and long-term exposure Symptoms Symptoms of overexposure may be headache, dizziness, tiredness, nausea and vomiting. Sensitization No information available. Mutagenic effects No information available. Carcinogenicity Contains no ingredient listed as a carcinogen. Ethanol has been shown to be carcinogenic in long-term studies only when consumed as alcoholic beverage. Contains a suspected carcinogen. However, this component is not at a concentration considered for classification. Based on available data, the classification criteria are not met. Reproductive toxicity No information available. STOT - single exposure No information available. STOT - repeated exposure No information available. Neurological effects No information available. Aspiration Hazard No information available. SECTION 12. Ecological information Ecotoxicity Harmful to aquatic life _____________________________________________________________________________________________ Page 5 / 7 20432 - PTMScan® Phospho-Enrichment IMAC Fe-NTA Magnetic Revision Date: 2016-08-05 Beads _____________________________________________________________________________________________ Reactive Hazard No Clean Water Act This product does not contain any substances regulated as pollutants pursuant to the Clean Water Act (40 CFR 122.21 and 40 CFR 122.42). CERCLA This material, as supplied, does not contain any substances regulated as hazardous substances under the Comprehensive Environmental Response Compensation and Liability Act (CERCLA) (40 CFR 302) or the Superfund Amendments and Reauthorization Act (SARA) (40 CFR 355). There may be specific reporting requirements at the local, regional, or state level pertaining to releases of this material. California Proposition 65 Ethyl alcohol is only a considered a Proposition 65 developmental hazard when it is ingested as an alcoholic beverage. Chemical Name California Prop. 65 ethanol Carcinogen Developmental U.S. State Right-to-Know Regulations Chemical Name New Jersey Massachusetts Pennsylvania ethanol Listed U.S. FIFRA Label Information This product does not contain any substances regulated as pesticides. US Commerce Department - Export Administration Regulations Information This product does not contain any substances regulated under the Chemical Weapons Convention (CWC). U.S. Drug Enforcement Administration Information This product does not contain any substances regulated under the DEA. SECTION 16. Other information Revision Date: 2016-08-05 Disclaimer The information provided in this Safety Data Sheet is correct to the best of our knowledge, information and belief at the date of its publication. The information given is designed only as a guidance for safe handling, use, processing, storage, transportation, disposal and release and is not to be considered a warranty or quality specification. The information relates only to the specific material designated and may not be valid for such material used in combination with any other materials or in any process, unless specified in the text. End of Safety Data Sheet _____________________________________________________________________________________________ Page 7 / 7 20432 - PTMScan® Phospho-Enrichment IMAC Fe-NTA Magnetic Chemical Name Toxicity to algae Toxicity to fish Toxicity to daphnia and other aquatic invertebrates ethanol - LC50 100 mg/L (Pimephales EC50 2 mg/L (Daphnia magna) 48 h promelas) 96 h LC50 13400 - 15100 EC50 10800 mg/L (Daphnia magna) mg/L (Pimephales promelas) 96 h 24 h LC50 9268 - 14221 mg/L LC50 12.0 - 16.0 mL/L (Daphnia magna) 48 h (Oncorhynchus mykiss) 96 h Persistence and degradability No information available. Bioaccumulation No information available. Mobility No information available Chemical Name Octanol-Water Partition Coefficient ethanol -0.32 Other adverse effects No information available. SECTION 13. Disposal considerations Waste Disposal Methods Dispose of in accordance with all applicable national environmental laws and regulations. Disposal considerations Do not empty into drains; dispose of this material and its container in a safe way. SECTION 14. Transport information This material is not subject to regulation as a hazardous material for shipping. SECTION 15. Regulatory information North American Inventory Listing Chemical Name TSCA 8(b) TSCA 12(b) DSL NDSL ethanol Listed Not Listed Listed