General Information
Revision date
2019-12-06
Product name
Varlitinib
Product Synonyms
N4-[3-chloro-4-(2-thiazolylmethoxy)phenyl]-N6-[(4R)-4,5-dihydro-4-methyl-2-oxazolyl]-4,6-quinazolinediamine; ARRY-334543; olinediamine; ARRY-334543;
1.2.1 Relevant identified uses
For research use only, not for human or veterinary use
Emergency telephone
+1 (800)424-9300, +1 (703)527-3887
Icons in SDS
Company Information
company name
Cayman Chemical Company
GHS Information
Signal word
Warning
Hazard Codes
Hazard statements (CLP)
H302, H319, H335, H400, H410
Hazard statements
Code
Statements
H302
Harmful if swallowed
Section 2
SECTION 2: Hazards identification
Classification of the Substance or Mixture Acute Toxicity: Oral, Category 4 Serious Eye Damage/Eye Irritation, Category 2 Specific Target Organ Toxicity (single exposure), Category 3 Aquatic Toxicity (Acute), Category 1 Aquatic Toxicity (Chronic), Category 1
Signal word
Warning
Hazard statements
H302: Harmful if swallowed. H319: Causes serious eye irritation. H335: May cause respiratory irritation. H400: Very toxic to aquatic life. H410: Very toxic to aquatic life with long lasting effects.
Precautionary statements
P261: Avoid breathing {dust/fume/gas/mist/vapors/spray}. P264: Wash {hands} thoroughly after handling. P273: Avoid release to the environment. P280: Wear {protective gloves/protective clothing/eye protection/face protection}.
Response
P301+312 IF SWALLOWED P312 Call a POISON CENTER or doctor/physician if you feel unwell P304+340 IF INHALED Remove victim to fresh air and keep at rest in a position comfortable for breathing P305+351+338 IF IN EYES Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P330: Rinse mouth. P337+313: If eye irritation persists, get medical advice/attention. P391: Collect spillage.
Storage
Please refer to Section 7 for Storage and Section 13 for Disposal information.
Potential health effects
Causes serious eye irritation. Causes skin irritation. Harmful if swallowed. Material may be irritating to the mucous membranes and upper respiratory tract. May be harmful by inhalation or skin absorption. May cause respiratory system irritation. Very toxic to aquatic life with long lasting effects. To the best of our knowledge, the toxicological properties have not been thoroughly investigated.
2.1 Classification of the substance or mixture
Acute Toxicity: Oral, Category 4 Serious Eye Damage/Eye Irritation, Category 2 Specific Target Organ Toxicity (single exposure), Category 3 Aquatic Toxicity (Acute), Category 1 Aquatic Toxicity (Chronic), Category 1
