General Information
Revision date
2019-03-26
Product name
Romidepsin
Product Synonyms
cyclic (35->)-disulfide-cyclo[(2Z)-2-amino-2-butenoyl-L-valyl-3S-hydroxy-7-mercapto-4E-heptenoyl-D-valyl-D-cysteinyl]; FK 228; FR 901228; NSC 630176; alyl-D-cysteinyl]; FK 228; FR 901228; NSC 630176;
1.2.1 Relevant identified uses
For research use only, not for human or veterinary use
Emergency telephone
+1 (800)424-9300, +1 (703)527-3887
Icons in SDS
Company Information
company name
Cayman Chemical Company
GHS Information
Signal word
Danger
Hazard Codes
Hazard statements (CLP)
H301, H317, H341, H400, H410
Hazard statements
Code
Statements
H301
Toxic if swallowed
Section 2
SECTION 2: Hazards identification
Classification of the Substance or Mixture Acute Toxicity: Oral, Category 3 Skin Sensitization, Category 1 Germ Cell Mutagenicity, Category 2 Aquatic Toxicity (Acute), Category 1 Aquatic Toxicity (Chronic), Category 1
Signal word
Danger
Hazard statements
H301: Toxic if swallowed. H317: May cause an allergic skin reaction. H341: Suspected of causing genetic defects. H400: Very toxic to aquatic life. H410: Very toxic to aquatic life with long lasting effects.
Precautionary statements
P201: Obtain special instructions before use. P202: Do not handle until all safety precautions have been read and understood. P261: Avoid breathing {dust/fume/gas/mist/vapours/spray}. P264: Wash {hands} thoroughly after handling. P272: Contaminated work clothing should not be allowed out of the workplace. P273: Avoid release to the environment. P280: Wear {protective gloves/protective clothing/eye protection/face protection}.
Response
P301+310 IF SWALLOWED Immediately call a POISON CENTER or doctor/physician P302+352 IF ON SKIN Wash with plenty of soap and water P308+313 IF exposed or concerned Get medical attention/advice P330: Rinse mouth. P333+313: If skin irritation or rash occurs, seek medical advice/attention. P362+364: Take off contaminated clothing and wash it before reuse. P391: Collect spillage.
Storage
Please refer to Section 7 for Storage and Section 13 for Disposal information
Potential health effects
Material may be irritating to the mucous membranes and upper respiratory tract. May cause an allergic skin reaction. May be harmful by inhalation or skin absorption. May cause eye, skin, or respiratory system irritation. Suspected to cause genetic defects. Toxic if swallowed. Very toxic to aquatic life with long lasting effects. To the best of our knowledge, the toxicological properties have not been thoroughly investigated.
2.1 Classification of the substance or mixture
Acute Toxicity: Oral, Category 3 Skin Sensitization, Category 1 Germ Cell Mutagenicity, Category 2 Aquatic Toxicity (Acute), Category 1 Aquatic Toxicity (Chronic), Category 1
