General Information
Revision date
2014-11-26
Product name
Roflumilast
Product Synonyms
3-(cyclopropylmethoxy)-N-(3,5-dichloro-4-pyridinyl)-4-(difluoromethoxy)-benzamide; B 9302-107; BY 217; BYK 20869; Daxas;
CAS No.
162401-32-3
Emergency telephone
Within USA and Canada
Icons in SDS
Company Information
company name
Cayman Chemical Company
GHS Information
Signal word
Danger
Hazard Codes
Hazard statements (CLP)
H301, H335, H361, H362, H413
Hazard statements
Code
Statements
H301
Toxic if swallowed
Section 2
CLP CLASSIFICATION
2.1.1 Classification according to Regulation (EC) No 1272/2008 [CLP]:]] Acute Toxicity: Oral, Category 3 Toxic To Reproduction, Category 2 Toxic To Reproduction, Effects on or via lactation Target Organ Systemic Toxicity (single exposure), Category 3 Aquatic Toxicity (Chronic), Category 4
EU Classification
Directive 1999/45/EC T: Toxic Reproductive Hazard: 3
Hazard statements
R25, R53, R63, R64, R67 For full text of R- phrases: see SECTION 15. H301: Toxic if swallowed. H361: Suspected of damaging fertility or the unborn child. H362: May cause harm to breast-fed children. H335: May cause respiratory irritation. H413: May cause long lasting harmful effects to aquatic life.
2.2 Label elements
2.2.1 Labeling according to Regulation (EC) No 1272/2008 [CLP]:
Signal word
Danger
Precautionary statements
P264: Wash {hands} thoroughly after handling. P201: Obtain special instructions before use. P202: Do not handle until all safety precautions have been read and understood. P281: Use personal protective equipment as required. P263: Avoid contact during pregnancy/while nursing. P260: Do not breathe {dust/fume/gas/mist/vapours/spray}. P261: Avoid breathing {dust/fume/gas/mist/vapours/spray}. P273: Avoid release to the environment.
Response
P301+310 IF SWALLOWED Immediately call a POISON CENTER or doctor/physician P330: Rinse mouth. P308+313 IF exposed or concerned Get medical attention/advice P304+340 IF INHALED Remove victim to fresh air and keep at rest in a position comfortable for breathing P312: Call a {POISON CENTER/doctor/...} if you feel unwell.
Storage
Please refer to Section 7 for Storage and Section 13 for Disposal information. 2.2.2 Labeling according to Directive 1999/45/EC: T Reproductive Hazard: 3
Potential health effects
Material may be irritating to the mucous membranes and upper respiratory tract. May be harmful by inhalation or skin absorption. May cause eye, skin, or respiratory system irritation. May cause harm to breast-fed children. May cause respiratory irritation. May cause long lasting harmful effects to aquatic life. Suspected of damaging fertility or the unborn child. Toxic if swallowed. To the best of our knowledge, the toxicological properties have not been thoroughly investigated.
