General Information
Revision date
2018-03-13
Product name
Panobinostat
Product Synonyms
(2E)-N-hydroxy-3-[4-[[[2-(2-methyl-1H-indol-3-yl)ethyl]amino]methyl]phenyl]-2-propenamide; LBH-589;
CAS No.
404950-80-7
Icons in SDS
Company Information
company name
Cayman Chemical Company
GHS Information
Signal word
Danger
Hazard Codes
Hazard statements (CLP)
H301, H315, H318, H331, H373
Hazard statements
Code
Statements
H301
Toxic if swallowed
Section 2
2.1 Classification of the substance or mixture
Acute Toxicity: Inhalation, Category 3 Acute Toxicity: Oral, Category 3 Skin Corrosion/Irritation, Category 2 Serious Eye Damage/Eye Irritation, Category 1 Specific Target Organ Toxicity (repeated exposure), Category 2
Signal word
Danger
Hazard statements
H301: Toxic if swallowed. H315: Causes skin irritation. H318: Causes serious eye damage. H331: Toxic if inhaled. H373: May cause damage to {organs} through prolonged or repeated exposure.
Precautionary statements
P260: Do not breathe {dust/fume/gas/mist/vapours/spray}. P264: Wash {hands} thoroughly after handling. P280: Wear {protective gloves/protective clothing/eye protection/face protection}.
Response
P301+310 IF SWALLOWED P310 Immediately call a POISON CENTER or doctor/physician P302+352 IF ON SKIN Wash with plenty of soap and water P304+340 IF INHALED Remove victim to fresh air and keep at rest in a position comfortable for breathing P305+351+338 IF IN EYES Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P314: Get medical attention/advice if you feel unwell. P321: Specific treatment {see ... on this label}. P330: Rinse mouth. P332+313: If skin irritation occurs, get medical advice/attention. P362+364: Take off contaminated clothing and wash it before reuse.
Storage
Please refer to Section 7 for Storage and Section 13 for Disposal information.
Potential health effects
Causes skin irritation. Causes serious eye damage. Material may be irritating to the mucous membranes and upper respiratory tract. May be harmful by skin absorption. May cause damage to organs through prolonged or repeated exposure. May cause respiratory system irritation. Toxic if inhaled or swallowed.. To the best of our knowledge, the toxicological properties have not been thoroughly investigated.
