Ingenol-3-angelate

Cayman Chemical Company

Revision date : 2015-03-07

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GHS05 GHS06
Health risk rating 5
Safety risk rating 1
Environmental risk rating 1

General Information

Revision date

2015-03-07

Product name

Ingenol-3-angelate

Product Synonyms

(2Z)-(1aR,2S,5R,5aS,6S,8aS,9R,10aR)-1a,2,5,5a,6,9,10,10a-octahydro-5,5a-dihydroxy-4-(hydroxymethyl)-1,1,7,9-tetramethyl-11-oxo-1H-2,8a-methanocyclopenta[a]cyclopropa[e]cyclodecen-6-yl ester 2-methyl-2-butenoic acid; Ingenol Mebutate; 3-Ingenyl Angelate; PEP005; Picato®; 6-yl ester 2-methyl-2-butenoic acid; Ingenol Mebutate; 3-Ingenyl Angelate; PEP005; Picato®;

1.2.1 Relevant identified uses

For research use only, not for human or veterinary use

Emergency telephone

+1 (800)424-9300, +1 (703)527-3887

Icons in SDS

GHS05 GHS06

Company Information

company name

Cayman Chemical Company

GHS Information

Signal word

Danger

Hazard Codes

Hazard statements (CLP)

H300, H314, H330

Hazard statements

Code

Statements

H300

Fatal if swallowed

Section 2

SECTION 2: Hazards identification

According to Regulation (EC) No 1272/2008 [CLP Classification of the Substance or Mixture

Signal word

Danger

Hazard statements

H300: Fatal if swallowed. H314: Causes severe skin burns and eye damage. H330: Fatal if inhaled.

Precautionary statements

P260: Do not breathe {dust/fume/gas/mist/vapors/spray}. P264: Wash {hands} thoroughly after handling. P280: Wear {protective gloves/protective clothing/eye protection/face protection}. P284: Wear respiratory protection {}.

Response

P301+310 IF SWALLOWED Immediately call a POISON CENTER or doctor/physician P303+361+353 IF ON SKIN (or hair) Remove/take off immediately all contaminated clothing. Rinse skin with water/shower. P304+340 IF INHALED Remove victim to fresh air and keep at rest in a position comfortable for breathing P305+351+338 IF IN EYES Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P310: Immediately call a POISON CENTER or doctor/physician. P320: Specific treatment is urgent {see ... on this label}. P330: Rinse mouth. P363: Wash contaminated clothing before reuse.

Storage

Please refer to Section 7 for Storage and Section 13 for Disposal information.

Potential health effects

Causes severe skin burns and eye damage. Fatal if inhaled. Fatal if swallowed. Material may be irritating to the mucous membranes and upper respiratory tract. May be harmful by skin absorption. May cause respiratory system irritation. To the best of our knowledge, the toxicological properties have not been thoroughly investigated.

2.1 Classification of the substance or mixture

2.1.1 Classification according to Regulation (EC) No 1272/2008 [CLP]: Acute Toxicity: Inhalation, Category 2 Acute Toxicity: Oral, Category 2 Skin Corrosion/Irritation, Category 1A

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