Imatinib (mesylate)

Cayman Chemical Company

Revision date : 2012-08-24

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GHS07 GHS08
Health risk rating 5
Safety risk rating 1
Environmental risk rating 1

General Information

Revision date

2012-08-24

Product name

Imatinib (mesylate)

Product Synonyms

4-[(4-methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl

CAS No.

220127-57-1

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Company Information

company name

Cayman Chemical Company

GHS Information

Signal word

Danger

Hazard Codes

Hazard statements (CLP)

H335, H360

Hazard statements

Code

Statements

H335

May cause respiratory irritation

Section 2

2.1 Classification of the substance or mixture

Placard Key word

Hazard statements

Target Organ Systemic Toxicity (single Exclamation Warning May cause respiratory irritation,or may cause drowsiness exposure), Category 3 point and dizziness Toxic To Reproduction, Category 1B H335: May cause respiratory irritation. H360: May damage fertility or the unborn child.

Health hazards

Danger May damage fertility or the unborn child

Precautionary statements

P261: Avoid breathing dust/fume/gas/mist/vapours/spray. P201: Obtain special instructions before use. P202: Do not handle until all safety precautions have been read and understood. P281: Use personal protective equipment as required.

Response

P309+311: Call a POISON CENTER or doctor/physician if exposed or you feel unwell. P304+340 IF INHALED Remove victim to fresh air and keep at rest in a position comfortable for breathing. P308+313 IF exposed or concerned Get medical attention/advice

Storage

Please refer to Section 7 for Storage and Section 13 for Disposal information.

Principle Routes of Exposure

Inhalation? Yes Skin? Yes Eyes? Yes Ingestion? Yes Other: Injection

Potential health effects

Acute and Chronic) Causes respiratory system irritation. Material is irritating to the mucous membranes and upper respiratory tract. May be harmful by inhalation, ingestion, or skin absorption. May cause eye or skin irritation. May cause harm to the unborn child. May impair fertility. Target Organs: Reproductive system, Immune system, Kidneys, Liver. Signs and Symptoms Of Exposure: Exposure may cause: abdominal pain, athralgia, diarrhea, fluid retention, headache, muscle cramps, nausea, skin rash, tiredness, or vomiting. To the best of our knowledge, the toxicological properties have not been thoroughly investigated. Medical Conditions Generally Aggravated By No data available. Exposure:

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