Crizotinib-d5

Cayman Chemical Company

Revision date : 2019-01-14

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GHS08 GHS07
Health risk rating 4
Safety risk rating 1
Environmental risk rating 1

General Information

Revision date

2019-01-14

Product name

Crizotinib-d5

Product Synonyms

3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(4-piperidinyl-3,3,4,5,5-d5)-1H-pyrazol-4-yl]-2-pyridinamine;

1.2.1 Relevant identified uses

For research use only, not for human or veterinary use

Emergency telephone

+1 (800)424-9300, +1 (703)527-3887

Icons in SDS

GHS07 GHS08

Company Information

company name

Cayman Chemical Company

GHS Information

Signal word

Warning

Hazard Codes

Hazard statements (CLP)

H317, H319, H341

Hazard statements

Code

Statements

H317

May cause an allergic skin reaction

Section 2

SECTION 2: Hazards identification

Classification of the Substance or Mixture Serious Eye Damage/Eye Irritation, Category 2 Skin Sensitization, Category 1 Germ Cell Mutagenicity, Category 2

Signal word

Warning

Hazard statements

H317: May cause an allergic skin reaction. H319: Causes serious eye irritation. H341: Suspected of causing genetic defects.

Precautionary statements

P201: Obtain special instructions before use. P202: Do not handle until all safety precautions have been read and understood. P261: Avoid breathing {dust/fume/gas/mist/vapors/spray}. P264: Wash {hands} thoroughly after handling. P272: Contaminated work clothing should not be allowed out of the workplace. P280: Wear {protective gloves/protective clothing/eye protection/face protection}.

Response

P302+352 IF ON SKIN Wash with plenty of soap and water P305+351+338 IF IN EYES Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P308+313 IF exposed or concerned Get medical attention/advice P333+313: If skin irritation or rash occurs, seek medical advice/attention. P337+313: If eye irritation persists, get medical advice/attention. P362+364: Take off contaminated clothing and wash it before reuse.

Storage

Please refer to Section 7 for Storage and Section 13 for Disposal information.

Potential health effects

Causes serious eye irritation. Material may be irritating to the mucous membranes and upper respiratory tract. May be harmful by inhalation, ingestion, or skin absorption. May cause an allergic skin reaction. May cause skin or respiratory system irritation. Suspected of causing genetic defects. To the best of our knowledge, the toxicological properties have not been thoroughly investigated.

2.1 Classification of the substance or mixture

Serious Eye Damage/Eye Irritation, Category 2 Skin Sensitization, Category 1 Germ Cell Mutagenicity, Category 2

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