General Information
Revision date
2015-10-20
Product name
Bortezomib
Product Synonyms
B-[(1R)-3-methyl-1-[[(2S)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)amino]propyl]amino]butyl]-boro
CAS No.
179324-69-7
Emergency telephone
Within USA and Canada
Icons in SDS
Company Information
company name
Cayman Chemical Company
GHS Information
Signal word
Danger
Hazard Codes
Hazard statements (CLP)
H300, H315, H319, H361, H372, H411
Hazard statements
Code
Statements
H300
Fatal if swallowed
Section 2
2.1 Classification of the substance or mixture
Acute Toxicity: Oral, Category 1 Skin Corrosion/Irritation, Category 2 Serious Eye Damage/Eye Irritation, Category 2 Toxic To Reproduction, Category 2 Specific Target Organ Toxicity (repeated exposure), Category 1 Aquatic Toxicity (Chronic), Category 2
Signal word
Danger
Hazard statements
EUH070: Toxic by eye contact. H300: Fatal if swallowed. H315: Causes skin irritation. H319: Causes serious eye irritation. H361: Suspected of damaging fertility or the unborn child. H372: Causes damage to organs through prolonged or repeated exposure. H411: Toxic to aquatic life with long lasting effects.
Precautionary statements
P201: Obtain special instructions before use. P202: Do not handle until all safety precautions have been read and understood. P260: Do not breathe {dust/fume/gas/mist/vapors/spray}. P264: Wash {hands} thoroughly after handling. P273: Avoid release to the environment. P280: Wear {protective gloves/protective clothing/eye protection/face protection}. P281: Use personal protective equipment as required.
Response
P301+310 IF SWALLOWED Immediately call a POISON CENTER or doctor/physician P302+352 IF ON SKIN Wash with plenty of soap and water P305+351+338 IF IN EYES Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P308+313 IF exposed or concerned Get medical attention/advice P314: Get medical attention/advice if you feel unwell. P330: Rinse mouth. P332+313: If skin irritation occurs, get medical advice/attention. P337+313: If eye irritation persists, get medical advice/attention. P362: Take off contaminated clothing and wash before re-use. P391: Collect spillage.
Storage
Please refer to Section 7 for Storage and Section 13 for Disposal information.
Potential health effects
Causes damage to organs through prolonged or repeated exposure. Causes serious eye irritation. Causes skin irritation. Fatal if swallowed. Material may be irritating to the mucous membranes and upper respiratory tract. May be harmful by inhalation or skin absorption. May cause respiratory system irritation. Suspected of damaging fertility or the unborn child. Toxic to aquatic life with long lasting effects To the best of our knowledge, the toxicological properties have not been thoroughly investigated.