General Information
Revision date
2018-10-24
Product name
AZD 6244
Product Synonyms
5-[(4-bromo-2-chlorophenyl)amino]-4-fluoro-N-(2-hydroxyethoxy)-1-methyl-1H-benzimidazole-6-carboxamide; ARRY-142886; Cl 1,040; NSC 741O78; Selumetinib; carboxamide; ARRY-142886; Cl 1,040; NSC 741O78; Selumetinib;
1.2.1 Relevant identified uses
For research use only, not for human or veterinary use
Emergency telephone
+1 (800)424-9300, +1 (703)527-3887
Icons in SDS
Company Information
company name
Cayman Chemical Company
GHS Information
Signal word
Danger
Hazard Codes
Hazard statements (CLP)
H317, H318, H361, H373
Hazard statements
Code
Statements
H317
May cause an allergic skin reaction
Section 2
SECTION 2: Hazards identification
Classification of the Substance or Mixture Serious Eye Damage/Eye Irritation, Category 1 Skin Sensitization, Category 1 Toxic To Reproduction, Category 2 Specific Target Organ Toxicity (repeated exposure), Category 2
Signal word
Danger
Hazard statements
H317: May cause an allergic skin reaction. H318: Causes serious eye damage. H361: Suspected of damaging fertility or the unborn child. H373: May cause damage to {gastrointestinal, oral} through prolonged or repeated exposure.
Precautionary statements
P201: Obtain special instructions before use. P202: Do not handle until all safety precautions have been read and understood. P260: Do not breathe {dust/fume/gas/mist/vapors/spray}. P272: Contaminated work clothing should not be allowed out of the workplace. P280: Wear {protective gloves/protective clothing/eye protection/face protection}.
Response
P302+352 IF ON SKIN Wash with plenty of soap and water P305+351+338 IF IN EYES Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P308+313 IF exposed or concerned Get medical attention/advice P310: Immediately call a POISON CENTER or doctor/physician. P314: Get medical attention/advice if you feel unwell. P333+313: If skin irritation or rash occurs, seek medical advice/attention. P362+364: Take off contaminated clothing and wash it before reuse.
Storage
Please refer to Section 7 for Storage and Section 13 for Disposal information.
Potential health effects
Causes serious eye damage. Material may be irritating to the mucous membranes and upper respiratory tract. May be harmful by inhalation, ingestion, or skin absorption. May cause an allergic skin reaction. May cause damage to {gastrointestinal, oral} through prolonged or repeated exposure. May cause skin or respiratory system irritation. Suspected of damaging fertility or the unborn child. To the best of our knowledge, the toxicological properties have not been thoroughly investigated.
2.1 Classification of the substance or mixture
Serious Eye Damage/Eye Irritation, Category 1 Skin Sensitization, Category 1 Toxic To Reproduction, Category 2 Specific Target Organ Toxicity (repeated exposure), Category 2
