General Information
Revision date
2016-11-05
Product name
AG-120
Product Synonyms
(2S)-1-(4-cyano-2-pyridinyl)-5-oxo-L-prolyl-2-(2-chlorophenyl)-N-(3,3-difluorocyclobutyl)-N2-(5-fl uoro-3-pyridinyl)-glycinamide; Invosidenib;
CAS No.
1448347-49-6
Emergency telephone
Within USA and Canada
Icons in SDS
Company Information
company name
Cayman Chemical Company
GHS Information
Signal word
Danger
Hazard Codes
Hazard statements (CLP)
H315, H317, H318, H334, H335, H341, H400, H413
Hazard statements
Code
Statements
H315
Causes skin irritation
Section 2
2.1 Classification of the substance or mixture
Skin Corrosion/Irritation, Category 2 Serious Eye Damage/Eye Irritation, Category 1 Respiratory Sensitization, Category 1 Skin Sensitization, Category 1 Germ Cell Mutagenicity, Category 2 Specific Target Organ Toxicity (single exposure), Category 3 Aquatic Toxicity (Acute), Category 1 Aquatic Toxicity (Chronic), Category 4
Signal word
Danger
Hazard statements
H315: Causes skin irritation. H317: May cause an allergic skin reaction. H318: Causes serious eye damage. H334: May cause allergy or asthma symptoms or breathing difficulties if inhaled. H335: May cause respiratory irritation. H341: Suspected of causing genetic defects. H400: Very toxic to aquatic life. H413: May cause long lasting harmful effects to aquatic life.
Precautionary statements
P201: Obtain special instructions before use. P202: Do not handle until all safety precautions have been read and understood. P261: Avoid breathing {dust/fume/gas/mist/vapors/spray}. P264: Wash {hands} thoroughly after handling. P272: Contaminated work clothing should not be allowed out of the workplace. P273: Avoid release to the environment. P280: Wear {protective gloves/protective clothing/eye protection/face protection}. P285: In case of inadequate ventilation wear respiratory protection.
Response
P302+352 IF ON SKIN Wash with plenty of soap and water P304+340 IF INHALED Remove victim to fresh air and keep at rest in a position comfortable for breathing P305+351+338 IF IN EYES Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P308+313 IF exposed or concerned Get medical attention/advice P310: Immediately call a POISON CENTER or doctor/physician. P332+313: If skin irritation occurs, get medical advice/attention. P333+313: If skin irritation or rash occurs, seek medical advice/attention. P342+311: If experiencing respiratory symptoms call a POISON CENTER or doctor/physician. P362+364: Take off contaminated clothing and wash it before reuse. P391: Collect spillage.
Storage
Please refer to Section 7 for Storage and Section 13 for Disposal information.
Potential health effects
Causes serious eye damage. Causes skin irritation. Material may be irritating to the mucous membranes and upper respiratory tract. May be harmful by inhalation, ingestion, or skin absorption. May cause an allergic skin reaction. May cause allergy or asthma symptoms or breathing difficulties if inhaled. May cause eye or respiratory system irritation. May cause long lasting harmful effects to aquatic life. Suspected of causing genetic defects. Very toxic to aquatic life. To the best of our knowledge, the toxicological properties have not been thoroughly investigated.
