General Information
Revision date
2025-11-19
Product name
VX-809
Product Synonyms
3-[6-[[[1-(2,2-difluoro-1,3-benzodioxol-5-yl)cyclopropyl]carbonyl]amino]-3-methyl-2-pyridinyl]-benzoicacid Lumacaftor VRT-826809
CAS No.
936727-05-8
1.2.1 Relevant identified uses
This product is for research use - Not for human or veterinary diagnostic or therapeutic use
Emergency telephone
+1 (734) 971-3335, 800-424-9300
Icons in SDS
Company Information
company name
Cayman Chemical Co
GHS Information
Signal word
Danger
Hazard Codes
Hazard statements (CLP)
H301, H312, H315, H318, H335, H360, H372
Hazard statements
Code
Statements
H301
Toxic if swallowed
Section 2
SECTION 2: Hazards identification
NFPA Rating Classification of the substance or mixture d ~ GHS06 Skull and crossbones Acute toxicity - oral 3 H301 Toxic if swallowed d ~ GHS08 Health hazard Reproductive toxicity 1A H360 May damage fertility or the unborn child Specific target organ toxicity (repeated exposure) 1 H372 Causes damage to organs through prolonged or repeated exposure Contd. on page 2) US Contd. from page 1) d ~ GHS05 Corrosion Eye damage 1 H318 Causes serious eye damage d ~ GHS07 Acute toxicity - dermal 4 H312 Harmful in contact with skin Skin irritation 2 H315 Causes skin irritation Specific target organ toxicity (single exposure) 3 H335 May cause respiratory irritation
2.2 Label elements
The substance is classified and labeled according to the Globally Harmonized System (GHS).
Hazard pictograms
d ~ d ~ d ~ d ~ GHS05 GHS06 GHS07 GHS08
Signal word
Danger
Hazard statements
H301 Toxic if swallowed. H312 Harmful in contact with skin. H315 Causes skin irritation. H318 Causes serious eye damage. H360 May damage fertility or the unborn child. H335 May cause respiratory irritation. H372 Causes damage to organs through prolonged or repeated exposure.
Precautionary statements
P201 Obtain special instructions before use. P202 Do not handle until all safety precautions have been read and understood. P260 Do not breathe dust/fume/gas/mist/vapors/spray. P264 Wash thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P271 Use only outdoors or in a well-ventilated area. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection. P301+P310 If swallowed: Immediately call a poison center/doctor. P321 Specific treatment (see on this label). P330 Rinse mouth. P302+P352 If on skin: Wash with plenty of water. P304+P340 If inhaled: Remove person to fresh air and keep comfortable for breathing. P305+P351+P338 If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P308+P313 IF exposed or concerned: Get medical advice/attention. P312 Call a poison center/doctor if you feel unwell. P314 Get medical advice/attention if you feel unwell. P362+P364 Take off contaminated clothing and wash it before reuse. P332+P313 If skin irritation occurs: Get medical advice/attention. P403+P233 Store in a well-ventilated place. Keep container tightly closed. (Contd. on page 3) US (Contd. from page 2) P405 Store locked up. P501 Dispose of contents/container in accordance with local/regional/national/international regulations. · Information pertaining to particular dangers for man and environment
Classification system
· NFPA ratings (scale 0 - 4) Health = 3 0 Fire = 0 3 0 Reactivity = 0 · HMIS-ratings (scale 0 - 4) HEALTH *3 Health = *3 FIRE 0 Fire = 0 REACTIVITY 0 Reactivity = 0
PBT Substances
Not applicable
vPvB Substances
Not applicable
2.3 Other hazards
There are no adverse physical or health effects known that are not covered by the hazard classes of the Hazard Communications Standard. *
2.1 Classification of the substance or mixture
d ~ GHS06 Skull and crossbones Acute toxicity - oral 3 H301 Toxic if swallowed. d ~ GHS08 Health hazard Reproductive toxicity 1A H360 May damage fertility or the unborn child. Specific target organ toxicity (repeated exposure) 1 H372 Causes damage to organs through prolonged or repeated exposure. (Contd. on page 2) US (Contd. from page 1) d ~ GHS05 Corrosion Eye damage 1 H318 Causes serious eye damage. d ~ GHS07 Acute toxicity - dermal 4 H312 Harmful in contact with skin. Skin irritation 2 H315 Causes skin irritation. Specific target organ toxicity (single exposure) 3 H335 May cause respiratory irritation.