Rocuronium (bromide)

Hazard statements (CLP)

H301, H312, H317, H319, H330, H335, H361, H370, H372

Code

Statements

H301

Toxic if swallowed

SECTION 2: Hazards identification

NFPA Rating Classification of the substance or mixture d ~ GHS06 Skull and crossbones Acute toxicity - oral 3 H301 Toxic if swallowed Acute toxicity - inhalation 2 H330 Fatal if inhaled d ~ GHS08 Health hazard Reproductive toxicity 2 H361 Suspected of damaging fertility or the unborn child Specific target organ toxicity (single exposure) 1 H370 Causes damage to organs Specific target organ toxicity (repeated exposure) 1 H372 Causes damage to organs through prolonged or repeated exposure Contd. from page 1) d ~ GHS07 Acute toxicity - dermal 4 H312 Harmful in contact with skin Eye irritation 2A H319 Causes serious eye irritation Sensitization - skin 1 H317 May cause an allergic skin reaction Specific target organ toxicity (single exposure) 3 H335 May cause respiratory irritation

2.2 Label elements

The substance is classified and labeled according to the Globally Harmonized System (GHS).

Hazard pictograms

d ~ d ~ d ~ GHS06 GHS07 GHS08

Signal word

Danger

Hazard statements

H301 Toxic if swallowed. H312 Harmful in contact with skin. H330 Fatal if inhaled. H319 Causes serious eye irritation. H317 May cause an allergic skin reaction. H361 Suspected of damaging fertility or the unborn child. H370 Causes damage to organs. H335 May cause respiratory irritation. H372 Causes damage to organs through prolonged or repeated exposure.

Precautionary statements

P201 Obtain special instructions before use. P202 Do not handle until all safety precautions have been read and understood. P260 Do not breathe dust/fume/gas/mist/vapors/spray. P264 Wash thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P271 Use only outdoors or in a well-ventilated area. P272 Contaminated work clothing must not be allowed out of the workplace. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection. P284 [In case of inadequate ventilation] wear respiratory protection. P301+P310 If swallowed: Immediately call a poison center/doctor. P330 Rinse mouth. P302+P352 If on skin: Wash with plenty of water. P304+P340 If inhaled: Remove person to fresh air and keep comfortable for breathing. P305+P351+P338 If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P308+P313 IF exposed or concerned: Get medical advice/attention. P312 Call a poison center/doctor if you feel unwell. P314 Get medical advice/attention if you feel unwell. P320 Specific treatment is urgent (see on this label). P362+P364 Take off contaminated clothing and wash it before reuse. P333+P313 If skin irritation or rash occurs: Get medical advice/attention. P337+P313 If eye irritation persists: Get medical advice/attention. (Contd. from page 2) P403+P233 Store in a well-ventilated place. Keep container tightly closed. P405 Store locked up. P501 Dispose of contents/container in accordance with local/regional/national/international regulations. · Information pertaining to particular dangers for man and environment

Classification system

· NFPA ratings (scale 0 - 4) Health = 4 0 Fire = 0 4 0 Reactivity = 0 · HMIS-ratings (scale 0 - 4) HEALTH *4 Health = *4 FIRE 0 Fire = 0 REACTIVITY 0 Reactivity = 0

PBT Substances

Not applicable

vPvB Substances

Not applicable

2.3 Other hazards

There are no adverse physical or health effects known that are not covered by the hazard classes of the Hazard Communications Standard. *

2.1 Classification of the substance or mixture

d ~ GHS06 Skull and crossbones Acute toxicity - oral 3 H301 Toxic if swallowed. Acute toxicity - inhalation 2 H330 Fatal if inhaled. d ~ GHS08 Health hazard Reproductive toxicity 2 H361 Suspected of damaging fertility or the unborn child. Specific target organ toxicity (single exposure) 1 H370 Causes damage to organs. Specific target organ toxicity (repeated exposure) 1 H372 Causes damage to organs through prolonged or repeated exposure. (Contd. from page 1) d ~ GHS07 Acute toxicity - dermal 4 H312 Harmful in contact with skin. Eye irritation 2A H319 Causes serious eye irritation. Sensitization - skin 1 H317 May cause an allergic skin reaction. Specific target organ toxicity (single exposure) 3 H335 May cause respiratory irritation.