Raltitrexed

Hazard statements (CLP)

H301, H341, H360, H400

Code

Statements

H301

Toxic if swallowed

SECTION 2: Hazards identification

NFPA Rating Classification of the substance or mixture d ~ GHS06 Skull and crossbones Acute toxicity - oral 3 H301 Toxic if swallowed d ~ GHS08 Health hazard Germ cell mutagenicity 2 H341 Suspected of causing genetic defects Reproductive toxicity 1A H360 May damage fertility or the unborn child Contd. from page 1) d ~ GHS09 Environment Aquatic Acute 1 H400 Very toxic to aquatic life

2.2 Label elements

The substance is classified and labeled according to the Globally Harmonized System (GHS).

Hazard pictograms

d ~ d ~ d ~ GHS06 GHS08 GHS09

Signal word

Danger

Hazard statements

H301 Toxic if swallowed. H341 Suspected of causing genetic defects. H360 May damage fertility or the unborn child. H400 Very toxic to aquatic life.

Precautionary statements

P201 Obtain special instructions before use. P202 Do not handle until all safety precautions have been read and understood. P264 Wash thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P273 Avoid release to the environment. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection. P301+P310 If swallowed: Immediately call a poison center/doctor. P321 Specific treatment (see on this label). P330 Rinse mouth. P308+P313 IF exposed or concerned: Get medical advice/attention. P391 Collect spillage. P405 Store locked up. P501 Dispose of contents/container in accordance with local/regional/national/international regulations. · Information pertaining to particular dangers for man and environment

Classification system

· NFPA ratings (scale 0 - 4) Health = 2 0 Fire = 0 2 0 Reactivity = 0 · HMIS-ratings (scale 0 - 4) HEALTH *2 Health = *2 FIRE 0 Fire = 0 REACTIVITY 0 Reactivity = 0

PBT Substances

Not applicable

vPvB Substances

Not applicable (Contd. from page 2)

2.3 Other hazards

There are no adverse physical or health effects known that are not covered by the hazard classes of the Hazard Communications Standard. *

2.1 Classification of the substance or mixture

d ~ GHS06 Skull and crossbones Acute toxicity - oral 3 H301 Toxic if swallowed. d ~ GHS08 Health hazard Germ cell mutagenicity 2 H341 Suspected of causing genetic defects. Reproductive toxicity 1A H360 May damage fertility or the unborn child. (Contd. from page 1) d ~ GHS09 Environment Aquatic Acute 1 H400 Very toxic to aquatic life.