Oxaliplatin

Hazard statements (CLP)

H302, H302+H312, H312, H315, H317, H318, H334, H335, H340, H350, H360, H362, H372

Code

Statements

H302

Harmful if swallowed

SECTION 2: Hazards identification

NFPA Rating Classification of the substance or mixture d ~ GHS08 Health hazard Sensitization - respiratory 1 H334 May cause allergy or asthm a symptoms or breathing difficulties if inhaled Germ cell mutagenicity 1A H340 May cause genetic defects Carcinogenicity 1A H350 May cause cancer Reproductive toxicity 1A H360-H362 May damage fertility or the unborn child. May cause harm to breast-fed children Specific target organ toxicity (repeated exposure) 1 H372 Causes damage to organs through prolonged or repeated exposure Contd. from page 1) d ~ GHS05 Corrosion Eye damage 1 H318 Causes serious eye damage d ~ GHS07 Acute toxicity - oral 4 H302 Harmful if swallowed Acute toxicity - dermal 4 H312 Harmful in contact with skin Skin irritation 2 H315 Causes skin irritation Sensitization - skin 1 H317 May cause an allergic skin reaction Specific target organ toxicity (single exposure) 3 H335 May cause respiratory irritation

2.2 Label elements

The substance is classified and labeled according to the Globally Harmonized System (GHS).

Hazard pictograms

d ~ d ~ d ~ GHS05 GHS07 GHS08

Signal word

Danger

Hazard statements

H302+H312 Harmful if swallowed or in contact with skin. H315 Causes skin irritation. H318 Causes serious eye damage. H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled. H317 May cause an allergic skin reaction. H340 May cause genetic defects. H350 May cause cancer. H360-H362 May damage fertility or the unborn child. May cause harm to breast-fed children. H335 May cause respiratory irritation. H372 Causes damage to organs through prolonged or repeated exposure.

Precautionary statements

P201 Obtain special instructions before use. P202 Do not handle until all safety precautions have been read and understood. P260 Do not breathe dusts or mists. P263 Avoid contact during pregnancy and /while nursing. P264 Wash thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P271 Use only outdoors or in a well-ventilated area. P272 Contaminated work clothing must not be allowed out of the workplace. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection. P284 [In case of inadequate ventilation] wear respiratory protection. P301+P312 If swallowed: Call a poison center/doctor if you feel unwell. P302+P352 If on skin: Wash with plenty of water. P304+P340 If inhaled: Remove person to fresh air and keep comfortable for breathing. P305+P351+P338 If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. (Contd. from page 2) P310 Immediately call a poison center/doctor. P308+P313 IF exposed or concerned: Get medical advice/attention. P321 Specific treatment (see on this label). P314 Get medical advice/attention if you feel unwell. P330 Rinse mouth. P362+P364 Take off contaminated clothing and wash it before reuse. P333+P313 If skin irritation or rash occurs: Get medical advice/attention. P342+P311 If experiencing respiratory symptoms: Call a poison center/doctor. P403+P233 Store in a well-ventilated place. Keep container tightly closed. P405 Store locked up. P501 Dispose of contents/container in accordance with local/regional/national/international regulations. · Information pertaining to particular dangers for man and environment

Classification system

· NFPA ratings (scale 0 - 4) Health = 3 0 Fire = 0 3 0 Reactivity = 0 · HMIS-ratings (scale 0 - 4) HEALTH *3 Health = *3 FIRE 0 Fire = 0 REACTIVITY 0 Reactivity = 0

PBT Substances

Not applicable

vPvB Substances

Not applicable

2.3 Other hazards

There are no adverse physical or health effects known that are not covered by the hazard classes of the Hazard Communications Standard. *

2.1 Classification of the substance or mixture

d ~ GHS08 Health hazard Sensitization - respiratory 1 H334 May cause allergy or asthm a symptoms or breathing difficulties if inhaled. Germ cell mutagenicity 1A H340 May cause genetic defects. Carcinogenicity 1A H350 May cause cancer. Reproductive toxicity 1A H360-H362 May damage fertility or the unborn child. May cause harm to breast-fed children. Specific target organ toxicity (repeated exposure) 1 H372 Causes damage to organs through prolonged or repeated exposure. (Contd. from page 1) d ~ GHS05 Corrosion Eye damage 1 H318 Causes serious eye damage. d ~ GHS07 Acute toxicity - oral 4 H302 Harmful if swallowed. Acute toxicity - dermal 4 H312 Harmful in contact with skin. Skin irritation 2 H315 Causes skin irritation. Sensitization - skin 1 H317 May cause an allergic skin reaction. Specific target organ toxicity (single exposure) 3 H335 May cause respiratory irritation.