General Information
Revision date
2025-12-23
Product name
Mertansine
Product Synonyms
N2′-deacetyl-N2′-(3-mercapto-1-oxopropyl)-maytansine DM1 Emtansine
CAS No.
139504-50-0
1.2.1 Relevant identified uses
This product is for research use - Not for human or veterinary diagnostic or therapeutic use
Emergency telephone
+1 (734) 971-3335, 800-424-9300
Icons in SDS
Company Information
company name
Cayman Chemical Co
GHS Information
Signal word
Danger
Hazard Codes
Hazard statements (CLP)
H300, H300+H310, H310, H314, H340, H350, H360, H370, H372
Hazard statements
Code
Statements
H300
Fatal if swallowed
Section 2
SECTION 2: Hazards identification
NFPA Rating Classification of the substance or mixture d ~ GHS06 Skull and crossbones Acute toxicity - oral 1 H300 Fatal if swallowed Acute toxicity - dermal 1 H310 Fatal in contact with skin d ~ GHS08 Health hazard Germ cell mutagenicity 1B H340 May cause genetic defects Carcinogenicity 1B H350 May cause cancer Reproductive toxicity 1B H360 May damage fertility or the unborn child Specific target organ toxicity (single exposure) 1 H370 Causes damage to organs Specific target organ toxicity (repeated exposure) 1 H372 Causes damage to organs through prolonged or repeated exposure Contd. on page 2) US Contd. from page 1) d ~ GHS05 Corrosion Skin corrosion 1B H314 Causes severe skin burns and eye damage
2.2 Label elements
The substance is classified and labeled according to the Globally Harmonized System (GHS).
Hazard pictograms
d ~ d ~ d ~ GHS05 GHS06 GHS08
Signal word
Danger
Hazard statements
H300+H310 Fatal if swallowed or in contact with skin. H314 Causes severe skin burns and eye damage. H340 May cause genetic defects. H350 May cause cancer. H360 May damage fertility or the unborn child. H370 Causes damage to organs. H372 Causes damage to organs through prolonged or repeated exposure.
Precautionary statements
P201 Obtain special instructions before use. P202 Do not handle until all safety precautions have been read and understood. P260 Do not breathe dusts or mists. P262 Do not get in eyes, on skin, or on clothing. P264 Wash thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection. P301+P310 If swallowed: Immediately call a poison center/doctor. P321 Specific treatment (see on this label). P301+P330+P331 If swallowed: Rinse mouth. Do NOT induce vomiting. P303+P361+P353 If on skin (or hair): Take off immediately all contaminated clothing. Rinse skin with water [or shower]. P304+P340 If inhaled: Remove person to fresh air and keep comfortable for breathing. P305+P351+P338 If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P308+P313 IF exposed or concerned: Get medical advice/attention. P314 Get medical advice/attention if you feel unwell. P361+P364 Take off immediately all contaminated clothing and wash it before reuse. P405 Store locked up. P501 Dispose of contents/container in accordance with local/regional/national/international regulations. · Information pertaining to particular dangers for man and environment
Classification system
· NFPA ratings (scale 0 - 4) Health = 4 0 Fire = 0 4 0 Reactivity = 0 (Contd. on page 3) US (Contd. from page 2) · HMIS-ratings (scale 0 - 4) HEALTH *4 Health = *4 FIRE 0 Fire = 0 REACTIVITY 0 Reactivity = 0
PBT Substances
Not applicable
vPvB Substances
Not applicable
2.3 Other hazards
There are no adverse physical or health effects known that are not covered by the hazard classes of the Hazard Communications Standard. *
2.1 Classification of the substance or mixture
d ~ GHS06 Skull and crossbones Acute toxicity - oral 1 H300 Fatal if swallowed. Acute toxicity - dermal 1 H310 Fatal in contact with skin. d ~ GHS08 Health hazard Germ cell mutagenicity 1B H340 May cause genetic defects. Carcinogenicity 1B H350 May cause cancer. Reproductive toxicity 1B H360 May damage fertility or the unborn child. Specific target organ toxicity (single exposure) 1 H370 Causes damage to organs. Specific target organ toxicity (repeated exposure) 1 H372 Causes damage to organs through prolonged or repeated exposure. (Contd. on page 2) US (Contd. from page 1) d ~ GHS05 Corrosion Skin corrosion 1B H314 Causes severe skin burns and eye damage.