Indomethacin

Hazard statements (CLP)

H300, H300+H310, H310, H317, H334, H341, H360, H362, H372, H412

Code

Statements

H300

Fatal if swallowed

SECTION 2: Hazards identification

NFPA Rating Classification of the substance or mixture d ~ GHS06 Skull and crossbones Acute toxicity - oral 1 H300 Fatal if swallowed Acute toxicity - dermal 1 H310 Fatal in contact with skin d ~ GHS08 Health hazard Sensitization - respiratory 1 H334 May cause allergy or asthm a symptoms or breathing difficulties if inhaled Germ cell mutagenicity 2 H341 Suspected of causing genetic defects Reproductive toxicity 1A H360-H362 May damage fertility or the unborn child. May cause harm to breast-fed children Contd. on page 2) US Contd. from page 1) Specific target organ toxicity (repeated exposure) 1 H372 Causes damage to organs through prolonged or repeated exposure d ~ GHS07 Sensitization - skin 1 H317 May cause an allergic skin reaction Aquatic Chronic 3 H412 Harmful to aquatic life with long lasting effects

2.2 Label elements

The substance is classified and labeled according to the Globally Harmonized System (GHS).

Hazard pictograms

d ~ d ~ GHS06 GHS08

Signal word

Danger

Hazard statements

H300+H310 Fatal if swallowed or in contact with skin. H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled. H317 May cause an allergic skin reaction. H341 Suspected of causing genetic defects. H360-H362 May damage fertility or the unborn child. May cause harm to breast-fed children. H372 Causes damage to organs through prolonged or repeated exposure. H412 Harmful to aquatic life with long lasting effects.

Precautionary statements

P201 Obtain special instructions before use. P202 Do not handle until all safety precautions have been read and understood. P260 Do not breathe dusts or mists. P262 Do not get in eyes, on skin, or on clothing. P263 Avoid contact during pregnancy and /while nursing. P264 Wash thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P272 Contaminated work clothing must not be allowed out of the workplace. P273 Avoid release to the environment. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection. P284 [In case of inadequate ventilation] wear respiratory protection. P301+P310 If swallowed: Immediately call a poison center/doctor. P321 Specific treatment (see on this label). P330 Rinse mouth. P302+P352 If on skin: Wash with plenty of water. P304+P340 If inhaled: Remove person to fresh air and keep comfortable for breathing. P308+P313 IF exposed or concerned: Get medical advice/attention. P314 Get medical advice/attention if you feel unwell. P361+P364 Take off immediately all contaminated clothing and wash it before reuse. P333+P313 If skin irritation or rash occurs: Get medical advice/attention. P342+P311 If experiencing respiratory symptoms: Call a poison center/doctor. P405 Store locked up. P501 Dispose of contents/container in accordance with local/regional/national/international regulations. (Contd. on page 3) US (Contd. from page 2) · Information pertaining to particular dangers for man and environment

Classification system

· NFPA ratings (scale 0 - 4) Health = 4 0 Fire = 0 4 0 Reactivity = 0 · HMIS-ratings (scale 0 - 4) HEALTH *4 Health = *4 FIRE 0 Fire = 0 REACTIVITY 0 Reactivity = 0

PBT Substances

Not applicable

vPvB Substances

Not applicable

2.3 Other hazards

There are no adverse physical or health effects known that are not covered by the hazard classes of the Hazard Communications Standard.

2.1 Classification of the substance or mixture

d ~ GHS06 Skull and crossbones Acute toxicity - oral 1 H300 Fatal if swallowed. Acute toxicity - dermal 1 H310 Fatal in contact with skin. d ~ GHS08 Health hazard Sensitization - respiratory 1 H334 May cause allergy or asthm a symptoms or breathing difficulties if inhaled. Germ cell mutagenicity 2 H341 Suspected of causing genetic defects. Reproductive toxicity 1A H360-H362 May damage fertility or the unborn child. May cause harm to breast-fed children. (Contd. on page 2) US (Contd. from page 1) Specific target organ toxicity (repeated exposure) 1 H372 Causes damage to organs through prolonged or repeated exposure. d ~ GHS07 Sensitization - skin 1 H317 May cause an allergic skin reaction. Aquatic Chronic 3 H412 Harmful to aquatic life with long lasting effects.