Calicheamicin

Hazard statements (CLP)

H302, H315, H319, H335, H341, H361, H372

Code

Statements

H302

Harmful if swallowed

SECTION 2: Hazards identification

2.1 Classification of the substance or mixture

d ~ GHS08 Health hazard Germ Cell Mutagenicity 2 H341 Suspected of causing genetic defects. Toxic to Reproduction 2 H361 Suspected of damaging fertility or the unborn child. Specific Target Organ Toxicity - Repeated Exposure H372 Causes damage to organs through 1 prolonged or repeated exposure. d ~ GHS07 Acute Toxicity - Oral 4 H302 Harmful if swallowed. Skin Irritation 2 H315 Causes skin irritation. Eye Irritation 2A H319 Causes serious eye irritation. (Contd. from page 1) Specific Target Organ Toxicity - Single Exposure 3 H335 May cause respiratory irritation.

2.2 Label elements

The substance is classified and labeled according to the Globally Harmonized System (GHS).

Hazard pictograms

d ~ d ~ GHS07 GHS08

Signal word

Danger

Hazard statements

H302 Harmful if swallowed. H315 Causes skin irritation. H319 Causes serious eye irritation. H341 Suspected of causing genetic defects. H361 Suspected of damaging fertility or the unborn child. H335 May cause respiratory irritation. H372 Causes damage to organs through prolonged or repeated exposure.

Precautionary statements

P201 Obtain special instructions before use. P202 Do not handle until all safety precautions have been read and understood. P260 Do not breathe dust/fume/gas/mist/vapors/spray. P264 Wash thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P271 Use only outdoors or in a well-ventilated area. P280 Wear protective gloves/protective clothing/eye protection/face protection. P301+P312 If swallowed: Call a poison center/doctor if you feel unwell. P330 Rinse mouth. P302+P352 If on skin: Wash with plenty of water. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P305+P351+P338 If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P308+P313 IF exposed or concerned: Get medical advice/attention. P321 Specific treatment (see on this label). P314 Get medical advice/attention if you feel unwell. P362+P364 Take off contaminated clothing and wash it before reuse. P332+P313 If skin irritation occurs: Get medical advice/attention. P337+P313 If eye irritation persists: Get medical advice/attention. P403+P233 Store in a well-ventilated place. Keep container tightly closed. P405 Store locked up. P501 Dispose of contents/container in accordance with local/regional/national/international regulations.

Classification system

NFPA ratings (scale 0 - 4) Health = 2 0 Fire = 0 2 0 Reactivity = 0 (Contd. from page 2) · HMIS-ratings (scale 0 - 4) HEALTH 2 Health = 2 FIRE 0 Fire = 0 REACTIVITY 0 Reactivity = 0

PBT Substances

Not applicable

vPvB Substances

Not applicable