Amitriptyline (hydrochloride)

Hazard statements (CLP)

H301, H319, H361, H362, H370, H400, H410

Code

Statements

H301

Toxic if swallowed

SECTION 2: Hazards identification

NFPA Rating Classification of the substance or mixture d ~ GHS06 Skull and crossbones Acute toxicity - oral 3 H301 Toxic if swallowed d ~ GHS08 Health hazard Reproductive toxicity 2 H361-H362 Suspected of damaging fertility or the unborn child. May cause harm to breast- fed children Specific target organ toxicity (single exposure) 1 H370 Causes damage to organs Contd. on page 2) US Contd. from page 1) d ~ GHS09 Environment Aquatic Acute 1 H400 Very toxic to aquatic life Aquatic Chronic 1 H410 Very toxic to aquatic life with long lasting effects d ~ GHS07 Eye irritation 2A H319 Causes serious eye irritation

2.2 Label elements

The substance is classified and labeled according to the Globally Harmonized System (GHS).

Hazard pictograms

d ~ d ~ d ~ d ~ GHS06 GHS07 GHS08 GHS09

Signal word

Danger

Hazard statements

H301 Toxic if swallowed. H319 Causes serious eye irritation. H361-H362 Suspected of damaging fertility or the unborn child. May cause harm to breast-fed children. H370 Causes damage to organs. H410 Very toxic to aquatic life with long lasting effects.

Precautionary statements

P201 Obtain special instructions before use. P202 Do not handle until all safety precautions have been read and understood. P260 Do not breathe dusts or mists. P263 Avoid contact during pregnancy and /while nursing. P264 Wash thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P273 Avoid release to the environment. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection. P301+P310 If swallowed: Immediately call a poison center/doctor. P321 Specific treatment (see on this label). P330 Rinse mouth. P305+P351+P338 If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P308+P313 IF exposed or concerned: Get medical advice/attention. P337+P313 If eye irritation persists: Get medical advice/attention. P391 Collect spillage. P405 Store locked up. P501 Dispose of contents/container in accordance with local/regional/national/international regulations. (Contd. on page 3) US (Contd. from page 2) · Information pertaining to particular dangers for man and environment

Classification system

· NFPA ratings (scale 0 - 4) Health = 3 0 Fire = 0 3 0 Reactivity = 0 · HMIS-ratings (scale 0 - 4) HEALTH *3 Health = *3 FIRE 0 Fire = 0 REACTIVITY 0 Reactivity = 0

PBT Substances

Not applicable

vPvB Substances

Not applicable

2.3 Other hazards

There are no adverse physical or health effects known that are not covered by the hazard classes of the Hazard Communications Standard.

2.1 Classification of the substance or mixture

d ~ GHS06 Skull and crossbones Acute toxicity - oral 3 H301 Toxic if swallowed. d ~ GHS08 Health hazard Reproductive toxicity 2 H361-H362 Suspected of damaging fertility or the unborn child. May cause harm to breast- fed children. Specific target organ toxicity (single exposure) 1 H370 Causes damage to organs. (Contd. on page 2) US (Contd. from page 1) d ~ GHS09 Environment Aquatic Acute 1 H400 Very toxic to aquatic life. Aquatic Chronic 1 H410 Very toxic to aquatic life with long lasting effects. d ~ GHS07 Eye irritation 2A H319 Causes serious eye irritation.