SURE-SEAL ECH-1 LAP SEALANT

SECTION 2: Hazards identification

wwe Emergency Overview * % ¥ 0% *« Lt MIS Danger — Highly flammable liquid and vapor F 4 Warning — Causes skin irritation R 0 Warning — Causes serious eye irritation PpEt Warning — May be harmful if swallowed and enters airways ‘See. 8 Danger — May damage fertility or the unborn child Warning — May cause an allergic skin reaction Warning — Suspected of causing genetic defects (skin) Warning — May cause drowsiness and dizziness Warning — May cause damage to organs (liver, kidney, ear) through prolonged or repeated exposure

Principle Routes of Exposure

Inhalation, Skin absorption, Skin contact, Ingestion Target Organ Effects: This material (or a component) shortens the time of onset or worsens the liver and kidney damage induced by other chemicals. This material (or a component) shortens the time of onset or worsens the neurotoxic effects induced by other chemicals. Exposure to lethal concentrations of methanol has been shown to cause damage to organs including liver, kidneys, pancreas, heart, lungs and brain. Although this rarely occurs, survivors of severe intoxication may suffer from permanent neurological damage. Prolonged intentional toluene abuse may lead to damage to many organ systems having effects on: central and peripheral nervous systems, vision, hearing, liver, kidneys, heart and blood. Such abuse has been associated with brain damage characterized by disturbances in gait, personality changes and loss of memory. Comparable central nervous system effects have not been shown to result from occupational exposure to toluene. Prolonged intentional toluene abuse may lead to hearing loss progressing to deafness. In addition, while noise is known to cause hearing loss in humans, it has been suggested that workers exposed to organic solvents, including toluene, along with noise may suffer greater hearing loss than would be expected from exposure to noise alone. Overexposure to this material (or its components) has been suggested as a cause of the following effects in laboratory animals: mild, reversible liver effects; mild, reversible kidney effects, cardiac sensitization, respiratory tract damage (nose, throat and airways), testis damage, kidney damage. Overexposure to this material (or its components) has been suggested as a cause of the following effects in humans: central nervous system effects, cardiac sensitization, visual impairment, and kidney damage. Acute Effects Inhalation: Breathing of vapor or mist is possible. Breathing this material may be harmful. Symptoms usually occur at air concentrations higher than the recommended exposure limits (See Section 8). Prolonged or repeated breathing of dust may result in progressive and permanent lung disease (fibrosis), which may cause death from respiratory and/or heart failure. Symptoms include coughing and difficult breathing, which becomes worse with physical activity. Eye: Can cause severe eye irritation. Symptoms include stinging, tearing, redness and swelling of eyes. Can injure eye tissue. Skin: Can cause skin irritation. Prolonged or repeated contact may dry the skin. Symptoms may include redness, burning, and drying and cracking of the skin, burns and other skin damage. Passage of this material into the body through the skin is possible, and may add to toxic effects from breathing or swallowing. Ingestion: Swallowing this material may be harmful. This material can get into the lungs during swallowing or vomiting. This results in lung inflammation and other lung injury. Symptoms of Exposure: Signs and symptoms of exposure to this material through breathing, ingestion and/or passage of the material through the skin may include: metallic taste, mouth and throat irritation (soreness, dry or scratchy feeling, cough), stomach or intestinal upset (nausea, vomiting, diarrhea), irritation (nose, throat, airways), tight feeling in the chest, central nervous system excitation (giddiness, liveliness, light-headed feeling) followed by central nervous system depression (dizziness, drowsiness, weakness, fatigue, nausea, headache, unconsciousness) and other central nervous system effects, temporary changes in mood and behavior, leg cramps, muscle weakness, pain in the abdomen and lower back, respiratory depression (slowing of the breathing rate), blurred vision, cyanosis (causes blue coloring of the skin and nails from lack of oxygen), narcosis (dazed or sluggish feeling), visual impairment (including blindness), respiratory failure, coma and death. Carcinogenicity: This material (or a component) is listed as a carcinogen by the International Agency for Research on Cancer (IARC). In a study conducted by the National Toxicology Program (NTP), di (2-ethylhexyl) adipate caused liver tumors in female mice when fed to the animals for two years. There was an increase in tumors in male mice, however it was not clearly related to di (2- ethylhexyl) adipate exposure. It did not cause an increase in tumors in either male or female rats in the same study. The relevance of this study to humans is uncertain. There is no evidence that this chemical causes cancer in humans. Di (2- ethylhexyl) adipate is not listed as a carcinogen by NTP, IARC or the Occupational Safety and Health Administration (OSHA). Ethylbenzene has been shown to cause cancer in laboratory animals. The relevance of this finding to humans is uncertain. IARC has classified ethylbenzene as a possible human carcinogen. IARC and NTP have determined that there is sufficient evidence in humans for the carcinogenicity of inhaled crystalline silica in the form of quartz or cristobalite. In addition, IARC has determined that there is sufficient evidence for the carcinogenicity of quartz and cristabolite in experimental animals. Among individuals with silicosis, lung cancer occurs more frequently in those who smoke.

Medical Conditions Generally Aggravated by Exposure

Respiratory symptoms associated with pre-existing lung disorders and pre-existing heart disorders may be aggravated by exposure to this material.

Potential chronic health

Prolonged contact with skin can cause moderate irritation and dermatitis. Excessive inhalation of vapors can cause nasal and respiratory irritation and dizziness, weakness, fatigue nausea, headache, unconsciousness, and even death. Overexposure has caused damage to kidney, liver, eye, spleen, lung, brain, and nervous system in animals, and may cause eye damage, cardiac, liver, central nervous system abnormalities in humans.