Note: Ingredients listed on restricted chemical lists
EC/CAS
67-56-1
Name of the chemical
Methanol
Concentration
N/A
General Information
Revision date
2016-06-27
Product name
Cardinal Fixative
CAS No.
67-56-1
1.2.1 Relevant identified uses
NON INDUSTRIAL USE - Typically sold in small quantity for laboratory use, 1 gallon or less
Emergency telephone
INFOTRAC USA & Canada 107913
Icons in SDS
Company Information
company name
Cambridge Diagnostic Products, Inc
e-mail address of the competent person responsible for the Safety Data Sheet
techinfo@ecamco.com
GHS Information
Signal word
Danger
Hazard Codes
Hazard statements (CLP)
H225, H301, H370
Hazard statements
Code
Statements
H225
Highly Flammable liquid and vapour
Section 2
SECTION 2: Hazards identification
Flammable Liquids, Category 2 Acute Toxicity: Oral, Category 3 Acute Toxicity: Skin, Category 3 Acute Toxicity: Inhalation, Category 3 Specific Target Organ Toxicity (single exposure), Category 1
Signal word
Danger
Hazard statements
H225 - Highly flammable liquid and vapor. H301+311_331 - Toxic if swallowed, in contact with skin or if inhaled. H370 - Causes damage to organs Central Nervous System, Eye, Kidney, Liver, Optic Nerve, Skin and Respiratory System.
Precautionary statements
P233 - Keep container tightly closed. P210 - Keep away from heat/sparks/open flames/hot surfaces. - No smoking. P280 - Wear protective gloves/protective clothing/eye protection/face protection. P243 - Take precautionary measures against static discharge. P264 - Wash hands thoroughly after handling. P270 - Do not eat, drink or smoke when using this product. P271 - Use only outdoors or in a well-ventilated area. P260 - Do not breathe fume/gas/mist/vapors/spray .
Response
P370+378 - In case of fire, use dry sand, dry chemical or alcohol-resistant foam to extinguish. P361+364 - Take off immediately all contaminated clothing and wash it before reuse. P303+361+353 - IF ON SKIN (or hair): Remove/take off immediately all contaminated clothing. Rinse skin with water/shower. P302+352 - IF ON SKIN: Wash with plenty of soap and water. P301+310 - IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. P330 - Rinse mouth. P304+340 - IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P309+311 - Call a POISON CENTER or doctor/physician if exposed or you feel unwell.
Storage
P403+235 - Store in cool/well-ventilated place. P404 - Store in a closed container. P501 - Dispose of contents/container to an appropriate waste disposal plant. P403+233 - Store container tightly closed in well-ventilated place.
Potential health effects
Chronic: Prolonged or repeated skin contact may cause dermatitis. Chronic exposure (Acute and Chronic): may cause effects similar to those of acute exposure. Methanol is only very slowly eliminated from the body. Because of this slow elimination, methanol should be regarded as a cumulative poison. Though a single exposure may cause no effect, daily exposures may result in the accumulation of a harmful amount. Methanol has produced fetotoxicity in rats and teratogenicity in mice exposed by inhalation to high concentrations that did not produce significant maternal toxicity. Inhalation: Methanol is toxic and can very readily form extremely high vapor concentrations at room temperature. Inhalation is the most common route of occupational exposure. At first, methanol causes CNS depression with nausea, headache, vomiting, dizziness and incoordination. A time period with no obvious symptoms follows (typically 8-24 hrs). This latent period is followed by metabolic acidosis and severe visual effects which may include reduced reactivity and/or increased sensitivity to light, blurred, double and/or snowy vision, and blindness. Depending on the severity of exposure and the promptness of treatment, survivors may recover completely or may have permanent blindness, vision disturbances and/or nervous system effects. Skin Contact: Causes moderate skin irritation. May be absorbed through the skin in harmful amounts. Prolonged and/or repeated contact may cause defatting of the skin and dermatitis. Methanol can be absorbed through the skin, producing systemic effects that include visual disturbances. Eye Contact: May cause painful sensitization to light. Methanol is a mild to moderate eye irritant. Inhalation, ingestion or skin absorption of methanol can cause significant disturbances in vision, including blindness. Ingestion: May be fatal or cause blindness if swallowed. Aspiration hazard. Cannot be made non-poisonous. May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May cause systemic toxicity with acidosis. May cause central nervous system depression, characterized by excitement, followed by headache, dizziness, drowsiness, and nausea. Advanced stages may cause collapse, unconsciousness, coma and possible death due to respiratory failure. May cause cardiopulmonary system effects.